MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-[beta]

Transforming growth factor-[beta] (TGF-[beta]) plays central roles in endothelial-mesenchymal transition (EndMT) involved in development and pathogenesis. Although EndMT and epithelial-mesenchymal transition are similar processes, roles of microRNAs in EndMT are largely unknown. Here, we report that...

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Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2016-01, Vol.21 (1), p.99
Hauptverfasser:	Katsura, Akihiro, Suzuki, Hiroshi I, Ueno, Toshihide, Mihira, Hajime, Yamazaki, Tomoko, Yasuda, Takahiko, Watabe, Tetsuro, Mano, Hiroyuki, Yamada, Yoshitsugu, Miyazono, Kohei
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Actin CCL17 protein Chemokines CXCL16 protein Gene expression Genotype & phenotype Inflammation Interleukin 6 Mesenchyme MicroRNAs miRNA NF-κB protein Poly(A) Polyadenylation Signal transduction Transcription Transforming growth factor-b Tumor necrosis factor
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