Voltammetric, spectroscopic and thermal investigations of the interaction of levofloxacin with cysteine at physiological pH
In this study, levofloxacin (LEVOF) hemihydrate interaction with L-cysteine (RSH) was investigated by using square-wave voltammetry (SWV) in Britton–Robinson (B–R) buffer pH 7.4. Addition of the LEVOF to RSH solution resulted in dropping of the main reduction peak current of RSH (the current of merc...
Gespeichert in:
| Veröffentlicht in: | Russian journal of electrochemistry 2017-05, Vol.53 (5), p.469-478 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 478 |
|---|---|
| container_issue | 5 |
| container_start_page | 469 |
| container_title | Russian journal of electrochemistry |
| container_volume | 53 |
| creator | Biçer, Ender Nuertayi, Parouke |
| description | In this study, levofloxacin (LEVOF) hemihydrate interaction with L-cysteine (RSH) was investigated by using square-wave voltammetry (SWV) in Britton–Robinson (B–R) buffer pH 7.4. Addition of the LEVOF to RSH solution resulted in dropping of the main reduction peak current of RSH (the current of mercurous cysteine thiolate Hg
2
(RS)
2
). The vary in the peak current of Hg
2
(RS)
2
, after the adding of the LEVOF is indicated an interaction between RSH and LEVOF molecules. Moreover, the interaction between two molecules also confirmed with UV-Vis, FT-IR spectroscopic measurements and thermal analysis data. Binding constant of LEVOF with RSH was calculated by both voltammetric and UV-Vis spectroscopic data. |
| doi_str_mv | 10.1134/S1023193517050044 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1905468336</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1905468336</sourcerecordid><originalsourceid>FETCH-LOGICAL-c316t-5201f7c58c8207c95b8e81dba3a389c08ec45e1ba2191e1297291413c129292e3</originalsourceid><addsrcrecordid>eNp1UEtLAzEQDqJgrf4AbwGvrmaSfSRHKWqFggcf1yWdZtuU7WZNUrX4581SD4LIHGb4XsMMIefArgBEfv0EjAtQooCKFYzl-QEZQclkJkTOD9Oc6Gzgj8lJCGvGmKxAjcjXq2uj3mxM9BYvaegNRu8Cut4i1d2CxpXxG91S272bEO1SR-u6QF0zMAmNxmscsAFqzbtrWvep0Xb0w8YVxV2IxnaG6kj71S5Y17qlxRTYT0_JUaPbYM5--pi83N0-T6bZ7PH-YXIzy1BAGbOCM2gqLCRKzipUxVwaCYu5FlpIhUwazAsDc81BgQGuKq4gB4FpTGXEmFzsc3vv3rbpinrttr5LK2tQrMhLKUSZVLBXYbo_eNPUvbcb7Xc1sHr4cf3nx8nD956QtN3S-F_J_5q-AY29f1I</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1905468336</pqid></control><display><type>article</type><title>Voltammetric, spectroscopic and thermal investigations of the interaction of levofloxacin with cysteine at physiological pH</title><source>SpringerNature Journals</source><creator>Biçer, Ender ; Nuertayi, Parouke</creator><creatorcontrib>Biçer, Ender ; Nuertayi, Parouke</creatorcontrib><description>In this study, levofloxacin (LEVOF) hemihydrate interaction with L-cysteine (RSH) was investigated by using square-wave voltammetry (SWV) in Britton–Robinson (B–R) buffer pH 7.4. Addition of the LEVOF to RSH solution resulted in dropping of the main reduction peak current of RSH (the current of mercurous cysteine thiolate Hg
2
(RS)
2
). The vary in the peak current of Hg
2
(RS)
2
, after the adding of the LEVOF is indicated an interaction between RSH and LEVOF molecules. Moreover, the interaction between two molecules also confirmed with UV-Vis, FT-IR spectroscopic measurements and thermal analysis data. Binding constant of LEVOF with RSH was calculated by both voltammetric and UV-Vis spectroscopic data.</description><identifier>ISSN: 1023-1935</identifier><identifier>EISSN: 1608-3342</identifier><identifier>DOI: 10.1134/S1023193517050044</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Binding ; Buffers ; Chemistry ; Chemistry and Materials Science ; Cysteine ; Electrochemistry ; Fourier transforms ; Infrared radiation ; Infrared spectroscopy ; Mathematical analysis ; Physical Chemistry ; Spectroscopic analysis ; Thermal analysis ; Voltammetry</subject><ispartof>Russian journal of electrochemistry, 2017-05, Vol.53 (5), p.469-478</ispartof><rights>Pleiades Publishing, Ltd. 2017</rights><rights>Copyright Springer Science & Business Media 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-5201f7c58c8207c95b8e81dba3a389c08ec45e1ba2191e1297291413c129292e3</citedby><cites>FETCH-LOGICAL-c316t-5201f7c58c8207c95b8e81dba3a389c08ec45e1ba2191e1297291413c129292e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S1023193517050044$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S1023193517050044$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Biçer, Ender</creatorcontrib><creatorcontrib>Nuertayi, Parouke</creatorcontrib><title>Voltammetric, spectroscopic and thermal investigations of the interaction of levofloxacin with cysteine at physiological pH</title><title>Russian journal of electrochemistry</title><addtitle>Russ J Electrochem</addtitle><description>In this study, levofloxacin (LEVOF) hemihydrate interaction with L-cysteine (RSH) was investigated by using square-wave voltammetry (SWV) in Britton–Robinson (B–R) buffer pH 7.4. Addition of the LEVOF to RSH solution resulted in dropping of the main reduction peak current of RSH (the current of mercurous cysteine thiolate Hg
2
(RS)
2
). The vary in the peak current of Hg
2
(RS)
2
, after the adding of the LEVOF is indicated an interaction between RSH and LEVOF molecules. Moreover, the interaction between two molecules also confirmed with UV-Vis, FT-IR spectroscopic measurements and thermal analysis data. Binding constant of LEVOF with RSH was calculated by both voltammetric and UV-Vis spectroscopic data.</description><subject>Binding</subject><subject>Buffers</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Cysteine</subject><subject>Electrochemistry</subject><subject>Fourier transforms</subject><subject>Infrared radiation</subject><subject>Infrared spectroscopy</subject><subject>Mathematical analysis</subject><subject>Physical Chemistry</subject><subject>Spectroscopic analysis</subject><subject>Thermal analysis</subject><subject>Voltammetry</subject><issn>1023-1935</issn><issn>1608-3342</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp1UEtLAzEQDqJgrf4AbwGvrmaSfSRHKWqFggcf1yWdZtuU7WZNUrX4581SD4LIHGb4XsMMIefArgBEfv0EjAtQooCKFYzl-QEZQclkJkTOD9Oc6Gzgj8lJCGvGmKxAjcjXq2uj3mxM9BYvaegNRu8Cut4i1d2CxpXxG91S272bEO1SR-u6QF0zMAmNxmscsAFqzbtrWvep0Xb0w8YVxV2IxnaG6kj71S5Y17qlxRTYT0_JUaPbYM5--pi83N0-T6bZ7PH-YXIzy1BAGbOCM2gqLCRKzipUxVwaCYu5FlpIhUwazAsDc81BgQGuKq4gB4FpTGXEmFzsc3vv3rbpinrttr5LK2tQrMhLKUSZVLBXYbo_eNPUvbcb7Xc1sHr4cf3nx8nD956QtN3S-F_J_5q-AY29f1I</recordid><startdate>20170501</startdate><enddate>20170501</enddate><creator>Biçer, Ender</creator><creator>Nuertayi, Parouke</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20170501</creationdate><title>Voltammetric, spectroscopic and thermal investigations of the interaction of levofloxacin with cysteine at physiological pH</title><author>Biçer, Ender ; Nuertayi, Parouke</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-5201f7c58c8207c95b8e81dba3a389c08ec45e1ba2191e1297291413c129292e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Binding</topic><topic>Buffers</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Cysteine</topic><topic>Electrochemistry</topic><topic>Fourier transforms</topic><topic>Infrared radiation</topic><topic>Infrared spectroscopy</topic><topic>Mathematical analysis</topic><topic>Physical Chemistry</topic><topic>Spectroscopic analysis</topic><topic>Thermal analysis</topic><topic>Voltammetry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Biçer, Ender</creatorcontrib><creatorcontrib>Nuertayi, Parouke</creatorcontrib><collection>CrossRef</collection><jtitle>Russian journal of electrochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Biçer, Ender</au><au>Nuertayi, Parouke</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Voltammetric, spectroscopic and thermal investigations of the interaction of levofloxacin with cysteine at physiological pH</atitle><jtitle>Russian journal of electrochemistry</jtitle><stitle>Russ J Electrochem</stitle><date>2017-05-01</date><risdate>2017</risdate><volume>53</volume><issue>5</issue><spage>469</spage><epage>478</epage><pages>469-478</pages><issn>1023-1935</issn><eissn>1608-3342</eissn><abstract>In this study, levofloxacin (LEVOF) hemihydrate interaction with L-cysteine (RSH) was investigated by using square-wave voltammetry (SWV) in Britton–Robinson (B–R) buffer pH 7.4. Addition of the LEVOF to RSH solution resulted in dropping of the main reduction peak current of RSH (the current of mercurous cysteine thiolate Hg
2
(RS)
2
). The vary in the peak current of Hg
2
(RS)
2
, after the adding of the LEVOF is indicated an interaction between RSH and LEVOF molecules. Moreover, the interaction between two molecules also confirmed with UV-Vis, FT-IR spectroscopic measurements and thermal analysis data. Binding constant of LEVOF with RSH was calculated by both voltammetric and UV-Vis spectroscopic data.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1023193517050044</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1023-1935 |
| ispartof | Russian journal of electrochemistry, 2017-05, Vol.53 (5), p.469-478 |
| issn | 1023-1935 1608-3342 |
| language | eng |
| recordid | cdi_proquest_journals_1905468336 |
| source | SpringerNature Journals |
| subjects | Binding Buffers Chemistry Chemistry and Materials Science Cysteine Electrochemistry Fourier transforms Infrared radiation Infrared spectroscopy Mathematical analysis Physical Chemistry Spectroscopic analysis Thermal analysis Voltammetry |
| title | Voltammetric, spectroscopic and thermal investigations of the interaction of levofloxacin with cysteine at physiological pH |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T03%3A00%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Voltammetric,%20spectroscopic%20and%20thermal%20investigations%20of%20the%20interaction%20of%20levofloxacin%20with%20cysteine%20at%20physiological%20pH&rft.jtitle=Russian%20journal%20of%20electrochemistry&rft.au=Bi%C3%A7er,%20Ender&rft.date=2017-05-01&rft.volume=53&rft.issue=5&rft.spage=469&rft.epage=478&rft.pages=469-478&rft.issn=1023-1935&rft.eissn=1608-3342&rft_id=info:doi/10.1134/S1023193517050044&rft_dat=%3Cproquest_cross%3E1905468336%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1905468336&rft_id=info:pmid/&rfr_iscdi=true |