Construction of Fused Pyrrolidines and [beta]-Lactones by Carbene-Catalyzed C-N, C-C, and C-O Bond Formations

A carbene-catalyzed intermolecular C-N bond formation, which initiates a highly selective cascade reaction for the synthesis of pyrrolidine fused [beta]-lactones, is disclosed. The nitrogen-containing bicyclic [beta]-lactone products are obtained with good yields and excellent stereoselectivities. S...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-04, Vol.56 (15), p.4201
Hauptverfasser:	Wu, Xingxing, Hao, Lin, Zhang, Yuexia, Rakesh, Maiti, Reddi, Rambabu N, Yang, Song, Song, Bao-An, Chi, Yonggui Robin
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbenes Cascade chemical reactions Catalysts Chemical bonds Chemical reactions Chemical synthesis Lactones Nitrogen Nitrogen atoms Pyrrolidine Reaction products
Online-Zugang:	Volltext
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