Piezoelectric electrospun nanocomposite comprising Au NPs/PVDF for nerve tissue engineering
In this study, gold nanoparticles/Polyvinylidenefluoride (PVDF) composite electrospun mat with enhanced piezoelectricity were fabricated and characterized. Gold colloidal nanoparticles (Au NPs) were prepared via laser ablation of metallic targets in liquid media. The active Q‐switched Nd:YAG laser w...
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| Veröffentlicht in: | Journal of biomedical materials research. Part A 2017-07, Vol.105 (7), p.1984-1993 |
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| container_end_page | 1993 |
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| container_issue | 7 |
| container_start_page | 1984 |
| container_title | Journal of biomedical materials research. Part A |
| container_volume | 105 |
| creator | Motamedi, Asma S. Mirzadeh, Hamid Hajiesmaeilbaigi, Fereshteh Bagheri‐Khoulenjani, Shadab Shokrgozar, Mohammad A. |
| description | In this study, gold nanoparticles/Polyvinylidenefluoride (PVDF) composite electrospun mat with enhanced piezoelectricity were fabricated and characterized. Gold colloidal nanoparticles (Au NPs) were prepared via laser ablation of metallic targets in liquid media. The active Q‐switched Nd:YAG laser was used as an irradiation source. Then, PVDF was dissolved in Au NPs colloidal solution at 30% wt for the synthesis of Au NPs/PVDF composite nanofibers by electrospinning. The optical absorbance spectra of Au NPS and the polymeric solutions were obtained by the UV‐Visible spectroscopy. Moreover, the morphology of Au NPS, nanostructures of fibers and diameter size distribution of nanofibers were analyzed by Scanning Electron Microscopy, Field Emission Scanning Electron Microscopy, and Transmitted Electron Microscopy methods. The crystallinity and piezoelectricity of PVDF and Au NPs/PVDF composite nanofibers mats were measured by X‐Ray Diffraction and Fourier Transform Infrared methods. Subsequently, in vitro cytocompatibility was evaluated by MTT assay and the attachment and morphology of PC‐12 cells cultured on scaffolds were studied. It was found that laser ablated Au NPs can be used in electrospun nanofibers of PVDF with adequate structural properties and increase piezoelectricity of nanofibers which might be suitable for applying as nerve tissue engineering scaffolds. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1984–1993, 2017. |
| doi_str_mv | 10.1002/jbm.a.36050 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1903107112</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1903107112</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3970-d5271bca1278ac60241792860e2f21f1f3a35db2ca47cf03cca1a4c57079cd993</originalsourceid><addsrcrecordid>eNp90DtPwzAUBWALgWgpTOzIEiNK60ccx2MplIcKdAAWBstxnCpV4xQ7AZVfj0sKI5PP8OlY9wBwitEQI0RGy6waqiFNEEN7oI8ZI1EsEra_zbGIKBFJDxx5vww4IHIIeiQlLOGp6IO3eWm-arMyunGlhl2o_bq10Cpb67pa175sDNwmV_rSLuC4hY9zP5q_Xk1hUTtojfswsCm9bw00dlFaY1yAx-CgUCtvTnbvALxMr58nt9Hs6eZuMp5FmgqOopwRjjOtMOGp0gkiMeaCpAkypCC4wAVVlOUZ0SrmukBUB6pizTjiQudC0AE473rXrn5vjW_ksm6dDV9KLBDFiGNMgrrolA73eWcKGe6plNtIjOR2SBmGlEr-DBn02a6zzSqT_9nf5QIgHfgsV2bzX5e8v3wYd63fFwd-ng</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1903107112</pqid></control><display><type>article</type><title>Piezoelectric electrospun nanocomposite comprising Au NPs/PVDF for nerve tissue engineering</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Motamedi, Asma S. ; Mirzadeh, Hamid ; Hajiesmaeilbaigi, Fereshteh ; Bagheri‐Khoulenjani, Shadab ; Shokrgozar, Mohammad A.</creator><creatorcontrib>Motamedi, Asma S. ; Mirzadeh, Hamid ; Hajiesmaeilbaigi, Fereshteh ; Bagheri‐Khoulenjani, Shadab ; Shokrgozar, Mohammad A.</creatorcontrib><description>In this study, gold nanoparticles/Polyvinylidenefluoride (PVDF) composite electrospun mat with enhanced piezoelectricity were fabricated and characterized. Gold colloidal nanoparticles (Au NPs) were prepared via laser ablation of metallic targets in liquid media. The active Q‐switched Nd:YAG laser was used as an irradiation source. Then, PVDF was dissolved in Au NPs colloidal solution at 30% wt for the synthesis of Au NPs/PVDF composite nanofibers by electrospinning. The optical absorbance spectra of Au NPS and the polymeric solutions were obtained by the UV‐Visible spectroscopy. Moreover, the morphology of Au NPS, nanostructures of fibers and diameter size distribution of nanofibers were analyzed by Scanning Electron Microscopy, Field Emission Scanning Electron Microscopy, and Transmitted Electron Microscopy methods. The crystallinity and piezoelectricity of PVDF and Au NPs/PVDF composite nanofibers mats were measured by X‐Ray Diffraction and Fourier Transform Infrared methods. Subsequently, in vitro cytocompatibility was evaluated by MTT assay and the attachment and morphology of PC‐12 cells cultured on scaffolds were studied. It was found that laser ablated Au NPs can be used in electrospun nanofibers of PVDF with adequate structural properties and increase piezoelectricity of nanofibers which might be suitable for applying as nerve tissue engineering scaffolds. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1984–1993, 2017.</description><identifier>ISSN: 1549-3296</identifier><identifier>EISSN: 1552-4965</identifier><identifier>DOI: 10.1002/jbm.a.36050</identifier><identifier>PMID: 28256789</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Absorbance ; Animals ; Au nanoparticles ; Biocompatibility ; composite nanofibers ; Crystallinity ; Electrochemical Techniques ; Electron microscopy ; Electrospinning ; Emission analysis ; Emission spectroscopy ; Field emission microscopy ; Fourier transforms ; Gold ; Gold - chemistry ; In vitro methods and tests ; Irradiation ; Laser ablation ; Mats ; Morphology ; Nanocomposites ; Nanocomposites - chemistry ; Nanofibers ; Nanoparticles ; Neodymium ; Nerve Tissue ; nerve tissue engineering ; PC12 Cells ; Piezoelectricity ; polyvinylidenefluoride nanofibrous scaffolds ; Polyvinyls - chemistry ; Rats ; Scanning electron microscopy ; Semiconductor lasers ; Size distribution ; Spectroscopy ; Spectrum analysis ; Tissue engineering ; Tissue Engineering - methods ; Tissue Scaffolds - chemistry ; X-ray diffraction ; YAG lasers</subject><ispartof>Journal of biomedical materials research. 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Part A</title><addtitle>J Biomed Mater Res A</addtitle><description>In this study, gold nanoparticles/Polyvinylidenefluoride (PVDF) composite electrospun mat with enhanced piezoelectricity were fabricated and characterized. Gold colloidal nanoparticles (Au NPs) were prepared via laser ablation of metallic targets in liquid media. The active Q‐switched Nd:YAG laser was used as an irradiation source. Then, PVDF was dissolved in Au NPs colloidal solution at 30% wt for the synthesis of Au NPs/PVDF composite nanofibers by electrospinning. The optical absorbance spectra of Au NPS and the polymeric solutions were obtained by the UV‐Visible spectroscopy. Moreover, the morphology of Au NPS, nanostructures of fibers and diameter size distribution of nanofibers were analyzed by Scanning Electron Microscopy, Field Emission Scanning Electron Microscopy, and Transmitted Electron Microscopy methods. The crystallinity and piezoelectricity of PVDF and Au NPs/PVDF composite nanofibers mats were measured by X‐Ray Diffraction and Fourier Transform Infrared methods. Subsequently, in vitro cytocompatibility was evaluated by MTT assay and the attachment and morphology of PC‐12 cells cultured on scaffolds were studied. It was found that laser ablated Au NPs can be used in electrospun nanofibers of PVDF with adequate structural properties and increase piezoelectricity of nanofibers which might be suitable for applying as nerve tissue engineering scaffolds. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1984–1993, 2017.</description><subject>Absorbance</subject><subject>Animals</subject><subject>Au nanoparticles</subject><subject>Biocompatibility</subject><subject>composite nanofibers</subject><subject>Crystallinity</subject><subject>Electrochemical Techniques</subject><subject>Electron microscopy</subject><subject>Electrospinning</subject><subject>Emission analysis</subject><subject>Emission spectroscopy</subject><subject>Field emission microscopy</subject><subject>Fourier transforms</subject><subject>Gold</subject><subject>Gold - chemistry</subject><subject>In vitro methods and tests</subject><subject>Irradiation</subject><subject>Laser ablation</subject><subject>Mats</subject><subject>Morphology</subject><subject>Nanocomposites</subject><subject>Nanocomposites - chemistry</subject><subject>Nanofibers</subject><subject>Nanoparticles</subject><subject>Neodymium</subject><subject>Nerve Tissue</subject><subject>nerve tissue engineering</subject><subject>PC12 Cells</subject><subject>Piezoelectricity</subject><subject>polyvinylidenefluoride nanofibrous scaffolds</subject><subject>Polyvinyls - chemistry</subject><subject>Rats</subject><subject>Scanning electron microscopy</subject><subject>Semiconductor lasers</subject><subject>Size distribution</subject><subject>Spectroscopy</subject><subject>Spectrum analysis</subject><subject>Tissue engineering</subject><subject>Tissue Engineering - methods</subject><subject>Tissue Scaffolds - chemistry</subject><subject>X-ray diffraction</subject><subject>YAG lasers</subject><issn>1549-3296</issn><issn>1552-4965</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90DtPwzAUBWALgWgpTOzIEiNK60ccx2MplIcKdAAWBstxnCpV4xQ7AZVfj0sKI5PP8OlY9wBwitEQI0RGy6waqiFNEEN7oI8ZI1EsEra_zbGIKBFJDxx5vww4IHIIeiQlLOGp6IO3eWm-arMyunGlhl2o_bq10Cpb67pa175sDNwmV_rSLuC4hY9zP5q_Xk1hUTtojfswsCm9bw00dlFaY1yAx-CgUCtvTnbvALxMr58nt9Hs6eZuMp5FmgqOopwRjjOtMOGp0gkiMeaCpAkypCC4wAVVlOUZ0SrmukBUB6pizTjiQudC0AE473rXrn5vjW_ksm6dDV9KLBDFiGNMgrrolA73eWcKGe6plNtIjOR2SBmGlEr-DBn02a6zzSqT_9nf5QIgHfgsV2bzX5e8v3wYd63fFwd-ng</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Motamedi, Asma S.</creator><creator>Mirzadeh, Hamid</creator><creator>Hajiesmaeilbaigi, Fereshteh</creator><creator>Bagheri‐Khoulenjani, Shadab</creator><creator>Shokrgozar, Mohammad A.</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope></search><sort><creationdate>201707</creationdate><title>Piezoelectric electrospun nanocomposite comprising Au NPs/PVDF for nerve tissue engineering</title><author>Motamedi, Asma S. ; Mirzadeh, Hamid ; Hajiesmaeilbaigi, Fereshteh ; Bagheri‐Khoulenjani, Shadab ; Shokrgozar, Mohammad A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3970-d5271bca1278ac60241792860e2f21f1f3a35db2ca47cf03cca1a4c57079cd993</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Absorbance</topic><topic>Animals</topic><topic>Au nanoparticles</topic><topic>Biocompatibility</topic><topic>composite nanofibers</topic><topic>Crystallinity</topic><topic>Electrochemical Techniques</topic><topic>Electron microscopy</topic><topic>Electrospinning</topic><topic>Emission analysis</topic><topic>Emission spectroscopy</topic><topic>Field emission microscopy</topic><topic>Fourier transforms</topic><topic>Gold</topic><topic>Gold - chemistry</topic><topic>In vitro methods and tests</topic><topic>Irradiation</topic><topic>Laser ablation</topic><topic>Mats</topic><topic>Morphology</topic><topic>Nanocomposites</topic><topic>Nanocomposites - chemistry</topic><topic>Nanofibers</topic><topic>Nanoparticles</topic><topic>Neodymium</topic><topic>Nerve Tissue</topic><topic>nerve tissue engineering</topic><topic>PC12 Cells</topic><topic>Piezoelectricity</topic><topic>polyvinylidenefluoride nanofibrous scaffolds</topic><topic>Polyvinyls - chemistry</topic><topic>Rats</topic><topic>Scanning electron microscopy</topic><topic>Semiconductor lasers</topic><topic>Size distribution</topic><topic>Spectroscopy</topic><topic>Spectrum analysis</topic><topic>Tissue engineering</topic><topic>Tissue Engineering - methods</topic><topic>Tissue Scaffolds - chemistry</topic><topic>X-ray diffraction</topic><topic>YAG lasers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Motamedi, Asma S.</creatorcontrib><creatorcontrib>Mirzadeh, Hamid</creatorcontrib><creatorcontrib>Hajiesmaeilbaigi, Fereshteh</creatorcontrib><creatorcontrib>Bagheri‐Khoulenjani, Shadab</creatorcontrib><creatorcontrib>Shokrgozar, Mohammad A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of biomedical materials research. Part A</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Motamedi, Asma S.</au><au>Mirzadeh, Hamid</au><au>Hajiesmaeilbaigi, Fereshteh</au><au>Bagheri‐Khoulenjani, Shadab</au><au>Shokrgozar, Mohammad A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Piezoelectric electrospun nanocomposite comprising Au NPs/PVDF for nerve tissue engineering</atitle><jtitle>Journal of biomedical materials research. Part A</jtitle><addtitle>J Biomed Mater Res A</addtitle><date>2017-07</date><risdate>2017</risdate><volume>105</volume><issue>7</issue><spage>1984</spage><epage>1993</epage><pages>1984-1993</pages><issn>1549-3296</issn><eissn>1552-4965</eissn><abstract>In this study, gold nanoparticles/Polyvinylidenefluoride (PVDF) composite electrospun mat with enhanced piezoelectricity were fabricated and characterized. Gold colloidal nanoparticles (Au NPs) were prepared via laser ablation of metallic targets in liquid media. The active Q‐switched Nd:YAG laser was used as an irradiation source. Then, PVDF was dissolved in Au NPs colloidal solution at 30% wt for the synthesis of Au NPs/PVDF composite nanofibers by electrospinning. The optical absorbance spectra of Au NPS and the polymeric solutions were obtained by the UV‐Visible spectroscopy. Moreover, the morphology of Au NPS, nanostructures of fibers and diameter size distribution of nanofibers were analyzed by Scanning Electron Microscopy, Field Emission Scanning Electron Microscopy, and Transmitted Electron Microscopy methods. The crystallinity and piezoelectricity of PVDF and Au NPs/PVDF composite nanofibers mats were measured by X‐Ray Diffraction and Fourier Transform Infrared methods. Subsequently, in vitro cytocompatibility was evaluated by MTT assay and the attachment and morphology of PC‐12 cells cultured on scaffolds were studied. It was found that laser ablated Au NPs can be used in electrospun nanofibers of PVDF with adequate structural properties and increase piezoelectricity of nanofibers which might be suitable for applying as nerve tissue engineering scaffolds. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1984–1993, 2017.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>28256789</pmid><doi>10.1002/jbm.a.36050</doi><tpages>10</tpages></addata></record> |
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| subjects | Absorbance Animals Au nanoparticles Biocompatibility composite nanofibers Crystallinity Electrochemical Techniques Electron microscopy Electrospinning Emission analysis Emission spectroscopy Field emission microscopy Fourier transforms Gold Gold - chemistry In vitro methods and tests Irradiation Laser ablation Mats Morphology Nanocomposites Nanocomposites - chemistry Nanofibers Nanoparticles Neodymium Nerve Tissue nerve tissue engineering PC12 Cells Piezoelectricity polyvinylidenefluoride nanofibrous scaffolds Polyvinyls - chemistry Rats Scanning electron microscopy Semiconductor lasers Size distribution Spectroscopy Spectrum analysis Tissue engineering Tissue Engineering - methods Tissue Scaffolds - chemistry X-ray diffraction YAG lasers |
| title | Piezoelectric electrospun nanocomposite comprising Au NPs/PVDF for nerve tissue engineering |
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