OP0158 Mitochondrial Genetic Variation and Susceptibility To Gout in Polynesians

BackgroundMitochondria appear to play a central role in the induction of an NLRP3 inflammatory response, an immune response critical for the development of gouty pathology. Mitochondria are in part self-encoding, possessing a 16.5 kB circular genome which encodes 36 genes. Therefore mitochondrial ge...

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Veröffentlicht in:	Annals of the rheumatic diseases 2016-06, Vol.75 (Suppl 2), p.115-116
Hauptverfasser:	Merriman, T.R., Gosling, A., Boocock, J., Dalbeth, N., Stamp, L., Stahl, E., Choi, H., Matisoo-Smith, L.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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