AB0807 Gout in Rural Area in Sub-Saharan Africa: A Comparison between Patients Coming from Rural and Urban Areas, in An Urban Tertiary Healthcare Center in Cameroon
BackgroundGout, the disease of kings is seen today in both urban and rural areas. However, few data are available on the characteristics of gout in the rural area, especially in sub-Saharan Africa.ObjectivesTo evaluate the differences between gouty patients in rural and urban areas in Cameroon, Cent...
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| Veröffentlicht in: | Annals of the rheumatic diseases 2016-06, Vol.75 (Suppl 2), p.1180 |
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| creator | Kemta Lekpa, F. Doualla, M.S. Singwe-Ngandeu, M. Namme Luma, H. |
| description | BackgroundGout, the disease of kings is seen today in both urban and rural areas. However, few data are available on the characteristics of gout in the rural area, especially in sub-Saharan Africa.ObjectivesTo evaluate the differences between gouty patients in rural and urban areas in Cameroon, Central Africa.MethodsWe performed a cross-sectional study in all 511 patients (96 women and 415 men) seen at General Hospital, Douala, Cameroon, between January 2004 and December 2013. The main demographic and clinical features of gouty patients living in rural and urban were compared. A p< 0.05 was considered statistically significant.ResultsThe baseline characteristics of patients are presented in Table 1. Patients living in rural areas were older, had an oligoarticular clinical presentation, more hyperuricemia and higher serum uric acid levels and a more frequent chronic inflammation compared to patients living in urban areas.Chronic kidney disease and dyslipidemia were more frequent in rural areas while obesity and hypertension were more frequent in urban areas.Table 1.Main baseline characteristics of patientsVariablesRural area (n=49)Urban area (n=462)pAge (years), mean ± SD60±12.0556±10.630.001SexMen34381 |
| doi_str_mv | 10.1136/annrheumdis-2016-eular.2481 |
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However, few data are available on the characteristics of gout in the rural area, especially in sub-Saharan Africa.ObjectivesTo evaluate the differences between gouty patients in rural and urban areas in Cameroon, Central Africa.MethodsWe performed a cross-sectional study in all 511 patients (96 women and 415 men) seen at General Hospital, Douala, Cameroon, between January 2004 and December 2013. The main demographic and clinical features of gouty patients living in rural and urban were compared. A p< 0.05 was considered statistically significant.ResultsThe baseline characteristics of patients are presented in Table 1. Patients living in rural areas were older, had an oligoarticular clinical presentation, more hyperuricemia and higher serum uric acid levels and a more frequent chronic inflammation compared to patients living in urban areas.Chronic kidney disease and dyslipidemia were more frequent in rural areas while obesity and hypertension were more frequent in urban areas.Table 1.Main baseline characteristics of patientsVariablesRural area (n=49)Urban area (n=462)pAge (years), mean ± SD60±12.0556±10.630.001SexMen34381<0.001Women1581Obesity242970.01Arthritis161820.001Tophi91830.01Presentation at diagnosisAcute gout25230<0.001Chronic gout24232<0.001Clinical presentation, nMonoarticular25230<0.001Oligoarticular22173<0.001Polyarticular2590.12Fever, n2190.21Elevated uric acid levels, n26231<0.001Serum uric acid, mean ± SD, mg/dL (μmol/L)84.68±3.2282.21±1.07<0.001MSU cristal (synovial fluid)†, n2200.21Acute phase reactants, nElevated CRP13151<0.001Elevated ESR28223<0.001Urate arthropathies, n‡662<0.001ConclusionsGout is characterized in patients living in rural area by a late age at onset and hyperuricemia higher compared to patients living in urban area. Cardiovascular risk factors are common. Further studies are needed to evaluate lifestyle changes in rural area.Disclosure of InterestNone declared]]></description><identifier>ISSN: 0003-4967</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/annrheumdis-2016-eular.2481</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><ispartof>Annals of the rheumatic diseases, 2016-06, Vol.75 (Suppl 2), p.1180</ispartof><rights>2016, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2016 (c) 2016, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/75/Suppl_2/1180.1.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/75/Suppl_2/1180.1.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,780,784,23571,27924,27925,77600,77631</link.rule.ids></links><search><creatorcontrib>Kemta Lekpa, F.</creatorcontrib><creatorcontrib>Doualla, M.S.</creatorcontrib><creatorcontrib>Singwe-Ngandeu, M.</creatorcontrib><creatorcontrib>Namme Luma, H.</creatorcontrib><title>AB0807 Gout in Rural Area in Sub-Saharan Africa: A Comparison between Patients Coming from Rural and Urban Areas, in An Urban Tertiary Healthcare Center in Cameroon</title><title>Annals of the rheumatic diseases</title><description><![CDATA[BackgroundGout, the disease of kings is seen today in both urban and rural areas. However, few data are available on the characteristics of gout in the rural area, especially in sub-Saharan Africa.ObjectivesTo evaluate the differences between gouty patients in rural and urban areas in Cameroon, Central Africa.MethodsWe performed a cross-sectional study in all 511 patients (96 women and 415 men) seen at General Hospital, Douala, Cameroon, between January 2004 and December 2013. The main demographic and clinical features of gouty patients living in rural and urban were compared. A p< 0.05 was considered statistically significant.ResultsThe baseline characteristics of patients are presented in Table 1. Patients living in rural areas were older, had an oligoarticular clinical presentation, more hyperuricemia and higher serum uric acid levels and a more frequent chronic inflammation compared to patients living in urban areas.Chronic kidney disease and dyslipidemia were more frequent in rural areas while obesity and hypertension were more frequent in urban areas.Table 1.Main baseline characteristics of patientsVariablesRural area (n=49)Urban area (n=462)pAge (years), mean ± SD60±12.0556±10.630.001SexMen34381<0.001Women1581Obesity242970.01Arthritis161820.001Tophi91830.01Presentation at diagnosisAcute gout25230<0.001Chronic gout24232<0.001Clinical presentation, nMonoarticular25230<0.001Oligoarticular22173<0.001Polyarticular2590.12Fever, n2190.21Elevated uric acid levels, n26231<0.001Serum uric acid, mean ± SD, mg/dL (μmol/L)84.68±3.2282.21±1.07<0.001MSU cristal (synovial fluid)†, n2200.21Acute phase reactants, nElevated CRP13151<0.001Elevated ESR28223<0.001Urate arthropathies, n‡662<0.001ConclusionsGout is characterized in patients living in rural area by a late age at onset and hyperuricemia higher compared to patients living in urban area. Cardiovascular risk factors are common. Further studies are needed to evaluate lifestyle changes in rural area.Disclosure of InterestNone declared]]></description><issn>0003-4967</issn><issn>1468-2060</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpNkUFOwzAQRS0EEqVwB0vdErBjx3HYhQhapEogWtbWJHFoqsQpk0SIHRuuwsE4CQntgpU1M1_Po3mEzDi74lyoa3AON7av87L1fMaVZ_sK8MqXmh-RCZdKD23FjsmEMSY8GanwlJy17XYomeZ6Qr7jW6ZZ-PP5NW_6jpaOPvcIFY3Rwlit-tRbwQYQHI0LLDO4oTFNmnoHWLaNo6nt3q119Am60rquHWele6UFNvWBBS6nL5iOhIHaXo7c2B1aa4tdCfhBFxaqbpMBWpoMIItjLIHaYtO4c3JSQNXai8M7Jev7u3Wy8JaP84ckXnppGGgP8kIFgVSR0DJULArzrADFfaVyP-B5mvuaAxOWZ75kmQzD4QQp92XoCy2UVmJKZnvsDpu33rad2TY9uuFHwyPGNRdC6iGl9qm03podlvWwvuHMjErMPyVmVGL-lJhRifgFvzWEIg</recordid><startdate>201606</startdate><enddate>201606</enddate><creator>Kemta Lekpa, F.</creator><creator>Doualla, M.S.</creator><creator>Singwe-Ngandeu, M.</creator><creator>Namme Luma, H.</creator><general>BMJ Publishing Group LTD</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>201606</creationdate><title>AB0807 Gout in Rural Area in Sub-Saharan Africa: A Comparison between Patients Coming from Rural and Urban Areas, in An Urban Tertiary Healthcare Center in Cameroon</title><author>Kemta Lekpa, F. ; Doualla, M.S. ; Singwe-Ngandeu, M. ; Namme Luma, H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b758-adf65546938476097dcfa61266d251dbd281a03e1c240c477818b124723836863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kemta Lekpa, F.</creatorcontrib><creatorcontrib>Doualla, M.S.</creatorcontrib><creatorcontrib>Singwe-Ngandeu, M.</creatorcontrib><creatorcontrib>Namme Luma, H.</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Annals of the rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kemta Lekpa, F.</au><au>Doualla, M.S.</au><au>Singwe-Ngandeu, M.</au><au>Namme Luma, H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>AB0807 Gout in Rural Area in Sub-Saharan Africa: A Comparison between Patients Coming from Rural and Urban Areas, in An Urban Tertiary Healthcare Center in Cameroon</atitle><jtitle>Annals of the rheumatic diseases</jtitle><date>2016-06</date><risdate>2016</risdate><volume>75</volume><issue>Suppl 2</issue><spage>1180</spage><pages>1180-</pages><issn>0003-4967</issn><eissn>1468-2060</eissn><coden>ARDIAO</coden><abstract><![CDATA[BackgroundGout, the disease of kings is seen today in both urban and rural areas. However, few data are available on the characteristics of gout in the rural area, especially in sub-Saharan Africa.ObjectivesTo evaluate the differences between gouty patients in rural and urban areas in Cameroon, Central Africa.MethodsWe performed a cross-sectional study in all 511 patients (96 women and 415 men) seen at General Hospital, Douala, Cameroon, between January 2004 and December 2013. The main demographic and clinical features of gouty patients living in rural and urban were compared. A p< 0.05 was considered statistically significant.ResultsThe baseline characteristics of patients are presented in Table 1. Patients living in rural areas were older, had an oligoarticular clinical presentation, more hyperuricemia and higher serum uric acid levels and a more frequent chronic inflammation compared to patients living in urban areas.Chronic kidney disease and dyslipidemia were more frequent in rural areas while obesity and hypertension were more frequent in urban areas.Table 1.Main baseline characteristics of patientsVariablesRural area (n=49)Urban area (n=462)pAge (years), mean ± SD60±12.0556±10.630.001SexMen34381<0.001Women1581Obesity242970.01Arthritis161820.001Tophi91830.01Presentation at diagnosisAcute gout25230<0.001Chronic gout24232<0.001Clinical presentation, nMonoarticular25230<0.001Oligoarticular22173<0.001Polyarticular2590.12Fever, n2190.21Elevated uric acid levels, n26231<0.001Serum uric acid, mean ± SD, mg/dL (μmol/L)84.68±3.2282.21±1.07<0.001MSU cristal (synovial fluid)†, n2200.21Acute phase reactants, nElevated CRP13151<0.001Elevated ESR28223<0.001Urate arthropathies, n‡662<0.001ConclusionsGout is characterized in patients living in rural area by a late age at onset and hyperuricemia higher compared to patients living in urban area. Cardiovascular risk factors are common. Further studies are needed to evaluate lifestyle changes in rural area.Disclosure of InterestNone declared]]></abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><doi>10.1136/annrheumdis-2016-eular.2481</doi></addata></record> |
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| title | AB0807 Gout in Rural Area in Sub-Saharan Africa: A Comparison between Patients Coming from Rural and Urban Areas, in An Urban Tertiary Healthcare Center in Cameroon |
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