THU0049 Involvement of Mitochondrial DNA in Rheumatoid Arthritis Pathogenesis Through Up-Regulation of RANK-L Expression by Neutrophils

BackgroundMitochondrial DNA (mtDNA) is a highly potent inflammatory trigger. It is found as a circulating factor in the blood of various inflammatory diseases. Among the cells implicated in the pathology of rheumatoid arthritis (RA), neutrophils possess the greatest cytotoxic potential, notably owin...

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Veröffentlicht in:	Annals of the rheumatic diseases 2015-06, Vol.74 (Suppl 2), p.209-210
Hauptverfasser:	Mitrovic, S., Contis, A., Faustin, B., Rossignol, R., Goizet, C., Truchetet, M.-E., Lazaro, E., Contin-Bordes, C., Duffau, P., Richez, C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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