AB0829 Demographics of Patients with New-Onset Psoriatic Arthritis: Real Life Data from an Inception Cohort
BackgroundPsoriatic arthritis is a complex disease with a wide range of manifestations. In this inception cohort of PsA patients we aimed to identify the initial manifestations as well as disease activity characteristics and compare with an unselected group of patients with longstanding disease.Meth...
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| Veröffentlicht in: | Annals of the rheumatic diseases 2015-06, Vol.74 (Suppl 2), p.1177-1178 |
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| creator | Kalyoncu, U. Yılmazer, B. Bayındır, Ö. Aksu, K. Dalkılıç, E. Öksüz, M.F. Tarhan, E.F. Can, M. Küçükşahin, O. Kimyon, G. Akyol, L. Onat, A.M. Kısacık, B. Erden, A. Omma, A. Ersözlü Bozkırlı, E.D. Özişler, C. Gönüllü, E. Masatlıoğlu Pehlevan, S. Solmaz, D. Çınar, M. Yıldırım Çetin, G. Tufan, A. Aydın Tufan, M. Kılıç, L. Erten, S. Kaşifoğlu, T. Özgen, M. Kasapoğlu Günal, E. Arslan, F. Pay, S. Kabasakal, Y. Aydın, S.Z. |
| description | BackgroundPsoriatic arthritis is a complex disease with a wide range of manifestations. In this inception cohort of PsA patients we aimed to identify the initial manifestations as well as disease activity characteristics and compare with an unselected group of patients with longstanding disease.MethodsPsART (Psoriatic Arthritis Registry of Turkey) is a prospective, multicentre study in Turkey on patients with PsA. Patients are consecutively recruited to this registry. Patients who have been newly diagnosed with PsA have been identified, and their characteristics were compared with longstanding disease.ResultsWithin 746 patients recruited, 111 (14.9%) had a new diagnosis for PsA. Patients in the inception cohort were significantly younger than the rest of the cohort (p=0.03) (table). Females were 53.2% of the inception and 66.8% of the non-inception cohort (p=0.007). For types of joint patterns, 14.4% of the inception cohort had only axial involvement whereas this was seen in 8.2% for the other group (p=0.05). The other joint patterns were comparable among groups. Both groups had similar tender and swollen joint counts, BASDAI and BASFI. Patient (p=0.002) and physician global assessments (p |
| doi_str_mv | 10.1136/annrheumdis-2015-eular.5045 |
| format | Article |
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In this inception cohort of PsA patients we aimed to identify the initial manifestations as well as disease activity characteristics and compare with an unselected group of patients with longstanding disease.MethodsPsART (Psoriatic Arthritis Registry of Turkey) is a prospective, multicentre study in Turkey on patients with PsA. Patients are consecutively recruited to this registry. Patients who have been newly diagnosed with PsA have been identified, and their characteristics were compared with longstanding disease.ResultsWithin 746 patients recruited, 111 (14.9%) had a new diagnosis for PsA. Patients in the inception cohort were significantly younger than the rest of the cohort (p=0.03) (table). Females were 53.2% of the inception and 66.8% of the non-inception cohort (p=0.007). For types of joint patterns, 14.4% of the inception cohort had only axial involvement whereas this was seen in 8.2% for the other group (p=0.05). The other joint patterns were comparable among groups. Both groups had similar tender and swollen joint counts, BASDAI and BASFI. Patient (p=0.002) and physician global assessments (p<0.001), fatigue (p=0.02), duration of morning stiffness (p=0.02) and CRP (p=0.05) were higher in the inception cohort. Female patients had higher patient global assessment and fatigue scores despite similar physician global assessment, swollen and tender joint counts, BASDAI, BASFI and CRP with males in non-inception cohort. For the inception cohort, there were no differences between the 2 genders.Table 1.Disease characteristics of the groupsInception cohortNon-inception cohortWhole groupFemalesMalesWhole groupFemalesMalesn1115952635424211age42.5 (12.3)44.4 (12.5)40.4 (11.7)45.5 (12.9)46.7 (13)43.1 (12.4)SJC2.7 (3.4)2.5 (3.2)3 (3.6)1.6 (2.8)1.5 (2.8)1.6 (2.7)TJC4.1 (4)3.8 (3.7)4.5 (4.2)3.4 (4.7)3.5 (4.8)3.4 (4.2)BASDAI*4.5 (2.4)4.3 (2.2)4.8 (2.5)3.7 (3.8)3.8 (4.3)3.5 (2.6)BASFI*3.2 (2.4)3 (2.3)3.4 (2.4)2.8 (2.7)2.7 (2.7)2.8 (2.7)Patient global*4.9 (2.5)4.7 (2.3)5.1 (2.6)3.9 (2.3)4 (2.3)3.5 (2.4)Physician global*4.2 (1.9)4 (1.6)4.4 (2.1)3.1 (2.1)3.1 (2)3 (2.2)fatigue*4.9 (2.5)5 (2.3)4.9 (2.7)4.2 (2.6)4.5 (2.5)3.7 (2.8)CRP (mg/lt)13. 4 (23.4)9.5 (16.5)18 (29.1)8.7 (16.2)8.6 (16.1)9 (16.5)*Data given on a scale between 0–10. There were missing data. The number of cases with available information are: BASDAI: 434, BASFI: 413; patient global assessment: 493; physician global assessment 440, fatigue: 506, CRP: 717, tender joint count: 677, swollen joint count: 672.ConclusionsMore patients present with sole axial involvement at the beginning, which may explain the higher disease activity agreed by the patient and the physician despite similar tender and swollen joint counts. Females may have a different perception of the disease with worse patient global assessments and fatigue in longstanding disease.Disclosure of InterestNone declared</description><identifier>ISSN: 0003-4967</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/annrheumdis-2015-eular.5045</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>Kidlington: Elsevier Limited</publisher><ispartof>Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.1177-1178</ispartof><rights>2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2015 (c) 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/74/Suppl_2/1177.3.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/74/Suppl_2/1177.3.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77569,77600</link.rule.ids></links><search><creatorcontrib>Kalyoncu, U.</creatorcontrib><creatorcontrib>Yılmazer, B.</creatorcontrib><creatorcontrib>Bayındır, Ö.</creatorcontrib><creatorcontrib>Aksu, K.</creatorcontrib><creatorcontrib>Dalkılıç, E.</creatorcontrib><creatorcontrib>Öksüz, M.F.</creatorcontrib><creatorcontrib>Tarhan, E.F.</creatorcontrib><creatorcontrib>Can, M.</creatorcontrib><creatorcontrib>Küçükşahin, O.</creatorcontrib><creatorcontrib>Kimyon, G.</creatorcontrib><creatorcontrib>Akyol, L.</creatorcontrib><creatorcontrib>Onat, A.M.</creatorcontrib><creatorcontrib>Kısacık, B.</creatorcontrib><creatorcontrib>Erden, A.</creatorcontrib><creatorcontrib>Omma, A.</creatorcontrib><creatorcontrib>Ersözlü Bozkırlı, E.D.</creatorcontrib><creatorcontrib>Özişler, C.</creatorcontrib><creatorcontrib>Gönüllü, E.</creatorcontrib><creatorcontrib>Masatlıoğlu Pehlevan, S.</creatorcontrib><creatorcontrib>Solmaz, D.</creatorcontrib><creatorcontrib>Çınar, M.</creatorcontrib><creatorcontrib>Yıldırım Çetin, G.</creatorcontrib><creatorcontrib>Tufan, A.</creatorcontrib><creatorcontrib>Aydın Tufan, M.</creatorcontrib><creatorcontrib>Kılıç, L.</creatorcontrib><creatorcontrib>Erten, S.</creatorcontrib><creatorcontrib>Kaşifoğlu, T.</creatorcontrib><creatorcontrib>Özgen, M.</creatorcontrib><creatorcontrib>Kasapoğlu Günal, E.</creatorcontrib><creatorcontrib>Arslan, F.</creatorcontrib><creatorcontrib>Pay, S.</creatorcontrib><creatorcontrib>Kabasakal, Y.</creatorcontrib><creatorcontrib>Aydın, S.Z.</creatorcontrib><title>AB0829 Demographics of Patients with New-Onset Psoriatic Arthritis: Real Life Data from an Inception Cohort</title><title>Annals of the rheumatic diseases</title><description>BackgroundPsoriatic arthritis is a complex disease with a wide range of manifestations. In this inception cohort of PsA patients we aimed to identify the initial manifestations as well as disease activity characteristics and compare with an unselected group of patients with longstanding disease.MethodsPsART (Psoriatic Arthritis Registry of Turkey) is a prospective, multicentre study in Turkey on patients with PsA. Patients are consecutively recruited to this registry. Patients who have been newly diagnosed with PsA have been identified, and their characteristics were compared with longstanding disease.ResultsWithin 746 patients recruited, 111 (14.9%) had a new diagnosis for PsA. Patients in the inception cohort were significantly younger than the rest of the cohort (p=0.03) (table). Females were 53.2% of the inception and 66.8% of the non-inception cohort (p=0.007). For types of joint patterns, 14.4% of the inception cohort had only axial involvement whereas this was seen in 8.2% for the other group (p=0.05). The other joint patterns were comparable among groups. Both groups had similar tender and swollen joint counts, BASDAI and BASFI. Patient (p=0.002) and physician global assessments (p<0.001), fatigue (p=0.02), duration of morning stiffness (p=0.02) and CRP (p=0.05) were higher in the inception cohort. Female patients had higher patient global assessment and fatigue scores despite similar physician global assessment, swollen and tender joint counts, BASDAI, BASFI and CRP with males in non-inception cohort. For the inception cohort, there were no differences between the 2 genders.Table 1.Disease characteristics of the groupsInception cohortNon-inception cohortWhole groupFemalesMalesWhole groupFemalesMalesn1115952635424211age42.5 (12.3)44.4 (12.5)40.4 (11.7)45.5 (12.9)46.7 (13)43.1 (12.4)SJC2.7 (3.4)2.5 (3.2)3 (3.6)1.6 (2.8)1.5 (2.8)1.6 (2.7)TJC4.1 (4)3.8 (3.7)4.5 (4.2)3.4 (4.7)3.5 (4.8)3.4 (4.2)BASDAI*4.5 (2.4)4.3 (2.2)4.8 (2.5)3.7 (3.8)3.8 (4.3)3.5 (2.6)BASFI*3.2 (2.4)3 (2.3)3.4 (2.4)2.8 (2.7)2.7 (2.7)2.8 (2.7)Patient global*4.9 (2.5)4.7 (2.3)5.1 (2.6)3.9 (2.3)4 (2.3)3.5 (2.4)Physician global*4.2 (1.9)4 (1.6)4.4 (2.1)3.1 (2.1)3.1 (2)3 (2.2)fatigue*4.9 (2.5)5 (2.3)4.9 (2.7)4.2 (2.6)4.5 (2.5)3.7 (2.8)CRP (mg/lt)13. 4 (23.4)9.5 (16.5)18 (29.1)8.7 (16.2)8.6 (16.1)9 (16.5)*Data given on a scale between 0–10. There were missing data. The number of cases with available information are: BASDAI: 434, BASFI: 413; patient global assessment: 493; physician global assessment 440, fatigue: 506, CRP: 717, tender joint count: 677, swollen joint count: 672.ConclusionsMore patients present with sole axial involvement at the beginning, which may explain the higher disease activity agreed by the patient and the physician despite similar tender and swollen joint counts. Females may have a different perception of the disease with worse patient global assessments and fatigue in longstanding disease.Disclosure of InterestNone declared</description><issn>0003-4967</issn><issn>1468-2060</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqVkM1OwzAQhC0EEqXwDpZ6TrETx3HgVFp-KlW0QnC2nHRNXDVxsB1V3LjwojwJKeXAldNqZ2d2pA-hESVjShN-qZrGVdDVa-OjmNA0gm6r3DglLD1CA8q46GVOjtGAEJJELOfZKTrzftOvRFAxQPXkhog4__r4nEFtX51qK1N6bDVeqWCgCR7vTKjwI-yiZeMh4JW3zvS3Ek9cqJwJxl_hJ1BbvDAa8EwFhbWzNVYNnjcltMHYBk9tZV04RydabT1c_M4herm7fZ4-RIvl_Xw6WUQFjbMsooJpzkQMcSJS0LyAnHEuygLUushinWRapFnSqxBDSoFCwnOesiIhZJ0RlgzR6PC3dfatAx_kxnau6SslzQkVhDGW9a7rg6t01nsHWrbO1Mq9S0rknq_8w1fu-cofvnLPt0_zQ7qoN_8KfgOCoIad</recordid><startdate>201506</startdate><enddate>201506</enddate><creator>Kalyoncu, U.</creator><creator>Yılmazer, B.</creator><creator>Bayındır, Ö.</creator><creator>Aksu, 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Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health & Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health & Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied & Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Annals of the rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kalyoncu, U.</au><au>Yılmazer, B.</au><au>Bayındır, Ö.</au><au>Aksu, K.</au><au>Dalkılıç, E.</au><au>Öksüz, M.F.</au><au>Tarhan, E.F.</au><au>Can, M.</au><au>Küçükşahin, O.</au><au>Kimyon, G.</au><au>Akyol, L.</au><au>Onat, A.M.</au><au>Kısacık, B.</au><au>Erden, A.</au><au>Omma, A.</au><au>Ersözlü Bozkırlı, E.D.</au><au>Özişler, C.</au><au>Gönüllü, E.</au><au>Masatlıoğlu Pehlevan, S.</au><au>Solmaz, D.</au><au>Çınar, M.</au><au>Yıldırım Çetin, G.</au><au>Tufan, A.</au><au>Aydın Tufan, M.</au><au>Kılıç, L.</au><au>Erten, S.</au><au>Kaşifoğlu, T.</au><au>Özgen, M.</au><au>Kasapoğlu Günal, E.</au><au>Arslan, F.</au><au>Pay, S.</au><au>Kabasakal, Y.</au><au>Aydın, S.Z.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>AB0829 Demographics of Patients with New-Onset Psoriatic Arthritis: Real Life Data from an Inception Cohort</atitle><jtitle>Annals of the rheumatic diseases</jtitle><date>2015-06</date><risdate>2015</risdate><volume>74</volume><issue>Suppl 2</issue><spage>1177</spage><epage>1178</epage><pages>1177-1178</pages><issn>0003-4967</issn><eissn>1468-2060</eissn><coden>ARDIAO</coden><abstract>BackgroundPsoriatic arthritis is a complex disease with a wide range of manifestations. In this inception cohort of PsA patients we aimed to identify the initial manifestations as well as disease activity characteristics and compare with an unselected group of patients with longstanding disease.MethodsPsART (Psoriatic Arthritis Registry of Turkey) is a prospective, multicentre study in Turkey on patients with PsA. Patients are consecutively recruited to this registry. Patients who have been newly diagnosed with PsA have been identified, and their characteristics were compared with longstanding disease.ResultsWithin 746 patients recruited, 111 (14.9%) had a new diagnosis for PsA. Patients in the inception cohort were significantly younger than the rest of the cohort (p=0.03) (table). Females were 53.2% of the inception and 66.8% of the non-inception cohort (p=0.007). For types of joint patterns, 14.4% of the inception cohort had only axial involvement whereas this was seen in 8.2% for the other group (p=0.05). The other joint patterns were comparable among groups. Both groups had similar tender and swollen joint counts, BASDAI and BASFI. Patient (p=0.002) and physician global assessments (p<0.001), fatigue (p=0.02), duration of morning stiffness (p=0.02) and CRP (p=0.05) were higher in the inception cohort. Female patients had higher patient global assessment and fatigue scores despite similar physician global assessment, swollen and tender joint counts, BASDAI, BASFI and CRP with males in non-inception cohort. For the inception cohort, there were no differences between the 2 genders.Table 1.Disease characteristics of the groupsInception cohortNon-inception cohortWhole groupFemalesMalesWhole groupFemalesMalesn1115952635424211age42.5 (12.3)44.4 (12.5)40.4 (11.7)45.5 (12.9)46.7 (13)43.1 (12.4)SJC2.7 (3.4)2.5 (3.2)3 (3.6)1.6 (2.8)1.5 (2.8)1.6 (2.7)TJC4.1 (4)3.8 (3.7)4.5 (4.2)3.4 (4.7)3.5 (4.8)3.4 (4.2)BASDAI*4.5 (2.4)4.3 (2.2)4.8 (2.5)3.7 (3.8)3.8 (4.3)3.5 (2.6)BASFI*3.2 (2.4)3 (2.3)3.4 (2.4)2.8 (2.7)2.7 (2.7)2.8 (2.7)Patient global*4.9 (2.5)4.7 (2.3)5.1 (2.6)3.9 (2.3)4 (2.3)3.5 (2.4)Physician global*4.2 (1.9)4 (1.6)4.4 (2.1)3.1 (2.1)3.1 (2)3 (2.2)fatigue*4.9 (2.5)5 (2.3)4.9 (2.7)4.2 (2.6)4.5 (2.5)3.7 (2.8)CRP (mg/lt)13. 4 (23.4)9.5 (16.5)18 (29.1)8.7 (16.2)8.6 (16.1)9 (16.5)*Data given on a scale between 0–10. There were missing data. The number of cases with available information are: BASDAI: 434, BASFI: 413; patient global assessment: 493; physician global assessment 440, fatigue: 506, CRP: 717, tender joint count: 677, swollen joint count: 672.ConclusionsMore patients present with sole axial involvement at the beginning, which may explain the higher disease activity agreed by the patient and the physician despite similar tender and swollen joint counts. Females may have a different perception of the disease with worse patient global assessments and fatigue in longstanding disease.Disclosure of InterestNone declared</abstract><cop>Kidlington</cop><pub>Elsevier Limited</pub><doi>10.1136/annrheumdis-2015-eular.5045</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-4967 |
| ispartof | Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.1177-1178 |
| issn | 0003-4967 1468-2060 |
| language | eng |
| recordid | cdi_proquest_journals_1901804447 |
| source | BMJ Journals - NESLi2 |
| title | AB0829 Demographics of Patients with New-Onset Psoriatic Arthritis: Real Life Data from an Inception Cohort |
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