THU0190 The Prediction Model for Methotrexate Efficacy Consisting of 9 SNPS Selected by Dmet Microarray Profiling in Japanese RA Patients

BackgroundEfficacy and toxicity of methotrexate (MTX) differs among individual patients, suggesting the influence of genetic variations in enzymes associated with MTX metabolism and folate metabolic pathway. We had investigated 1,971 polymorphisms of 246 enzymes/transporters relevant to the hepatoto...

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Veröffentlicht in:	Annals of the rheumatic diseases 2015-06, Vol.74 (Suppl 2), p.263-263
Hauptverfasser:	Kumagai, S., Tsuji, G., Ichise, Y., Umeda, R., Muta, A., Abe, K., Izumi, M., Uemura, Y., Uga, H., Kurata, H., Misaki, K., Onishi, A.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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