THU0389 A Multiple Dose Study of AMG 811 (Anti-IFN-Gamma) in Subjects with Systemic Lupus Erythematosus and Active Nephritis

BackgroundInterferon-gamma (IFN-g) is a pro-inflammatory cytokine that modulates the function of several important immune populations. Evidence from human and animal models suggests that increased levels of Type I and/or Type II IFN are associated with SLE.ObjectivesThis study assessed the safety, t...

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Veröffentlicht in:	Annals of the rheumatic diseases 2015-06, Vol.74 (Suppl 2), p.337
Hauptverfasser:	Martin, D.A., Amoura, Z., Romero-Diaz, J., Chong, Y.B., Sanchez-Guerrero, J., Chan, T., Arnold, G.E., Damore, M.A., Sohn, W., Chirmule, N., Chiu, K., Wang, C., Boedigheimer, M., Sullivan, B.A., Welcher, A., Kotzin, B., Chung, J.B.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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