THU0623-HPR Joint Hypermobility – is There a Correlation Between Muscle Cross Sectional Area and Muscle Strength?
BackgroundGeneralized Joint Hypermobility (GJH) is often underestimated and little is known about clinical implications and optimal treatment. Hypermobile persons are often restricted in performing sports or leisure activities, as well as during work, due to pain and disability (1). Adequate muscle...
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| Veröffentlicht in: | Annals of the rheumatic diseases 2015-06, Vol.74 (Suppl 2), p.1316-1317 |
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| description | BackgroundGeneralized Joint Hypermobility (GJH) is often underestimated and little is known about clinical implications and optimal treatment. Hypermobile persons are often restricted in performing sports or leisure activities, as well as during work, due to pain and disability (1). Adequate muscle strength for movement control might be an important issue to overcome these restrictions. However, little is known about muscle properties of women with GJH. Although it is commonly recognized that strength and muscle cross-sectional area (CSA) are related, the exact relationship seems complex and remains unclear.ObjectivesThe aim of the study was to analyze the correlation between muscle strength and muscle CSA in women with GJH.MethodsThis cross-sectional study included 52 hypermobile women (mean age 26.7±4.7 years, weight 62.4±10.8 kg, BMI 22.8±3.6 kg/m2) with a Beighton-score of six or more (2). Maximum isometric muscle strength for knee extensors and flexors was measured and calculated as maximal voluntary contraction (MVC) and rate of force development (RFD). Muscle CSA of thigh was measured at one third above knee using peripheral quantitative computer tomography (pQCT). Parameters were calculated as absolute values and related to body weight. Correlation coefficients according to Pearson (r) were calculated, as well as the coefficient of determination (r2) in percent. Significance level was set at p=0.05.ResultsFor the absolute values significant correlations were found between MVC and muscle CSA with r=0.46 (r2=21%, p |
| doi_str_mv | 10.1136/annrheumdis-2015-eular.3339 |
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Hypermobile persons are often restricted in performing sports or leisure activities, as well as during work, due to pain and disability (1). Adequate muscle strength for movement control might be an important issue to overcome these restrictions. However, little is known about muscle properties of women with GJH. Although it is commonly recognized that strength and muscle cross-sectional area (CSA) are related, the exact relationship seems complex and remains unclear.ObjectivesThe aim of the study was to analyze the correlation between muscle strength and muscle CSA in women with GJH.MethodsThis cross-sectional study included 52 hypermobile women (mean age 26.7±4.7 years, weight 62.4±10.8 kg, BMI 22.8±3.6 kg/m2) with a Beighton-score of six or more (2). Maximum isometric muscle strength for knee extensors and flexors was measured and calculated as maximal voluntary contraction (MVC) and rate of force development (RFD). Muscle CSA of thigh was measured at one third above knee using peripheral quantitative computer tomography (pQCT). Parameters were calculated as absolute values and related to body weight. Correlation coefficients according to Pearson (r) were calculated, as well as the coefficient of determination (r2) in percent. Significance level was set at p=0.05.ResultsFor the absolute values significant correlations were found between MVC and muscle CSA with r=0.46 (r2=21%, p<0.001) for knee extensors and r=0.29 (r2=9%, p=0.035) for flexors. Values related to body weigh showed comparable correlations for MVC and additional significant correlation between RFD of knee extensors and CSA with r=0.31 (r2=9%, p=0.028). Regarding strength, the correlation between MVC and RFD for extensors was significant at a middle level (r=0.52, r2=27%, p<0.001), as well as for flexors (r=0.56, r2=32%, p<0.001). Between flexors and extensors correlations were middle, with r=0.69 (r2=48%, p<0.001) for MVC and r=0.51 (r2=26%, p<0.001) for RFD. Finally, body weight was correlated with muscle CSA (r=0.52, r2=27%, p<0.001), only weak with MVC of extensors (r=0.26, r2=7%, p=0.059), but not with RFD of extensors (r=0.009).ConclusionsMaximum strength of knee extensors and flexors was correlated with muscle CSA of thigh, with values comparable to studies with healthy or exercising people (3). Correlations were highly significant, but on a low level with r2 from 9 to 21%. This indicates that muscle CSA is not solely responsible for the determination of adequate muscle strength. The fact that RFD of knee extensors was only correlated when related to body weight, may point to the importance of fibre type distribution and neuromuscular control (4). In contrast MVC is more dependent on muscle CSA. To conclude, muscle strength is a complex phenomenon, especially RFD and depends on various factors, not solely on muscle CSA.ReferencesSimmonds & Keer, Manual Therapy 2007:298-309.Remvig et al. The Journal of Rheumatology 2007:798-803.Remvig et al. The Journal of Rheumatology 2007:798-803.Jones et al. Sports Med 2008:987-994.Andersen & Aagard, Eur J Appl Physiol 2006:46-52.AcknowledgementsThe study was approved by the Ethics Committee of Canton Bern (222/12).Disclosure of InterestNone declared]]></description><identifier>ISSN: 0003-4967</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/annrheumdis-2015-eular.3339</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>Kidlington: Elsevier Limited</publisher><ispartof>Annals of the rheumatic diseases, 2015-06, Vol.74 (Suppl 2), p.1316-1317</ispartof><rights>2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>Copyright: 2015 (c) 2015, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/74/Suppl_2/1316.3.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/74/Suppl_2/1316.3.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23550,27901,27902,77343,77374</link.rule.ids></links><search><creatorcontrib>Luder, G.</creatorcontrib><creatorcontrib>Haehni, M.</creatorcontrib><creatorcontrib>Mueller Mebes, C.</creatorcontrib><creatorcontrib>Verra, M.L.</creatorcontrib><creatorcontrib>Aeberli, D.</creatorcontrib><creatorcontrib>Baeyens, J.-P.</creatorcontrib><title>THU0623-HPR Joint Hypermobility – is There a Correlation Between Muscle Cross Sectional Area and Muscle Strength?</title><title>Annals of the rheumatic diseases</title><description><![CDATA[BackgroundGeneralized Joint Hypermobility (GJH) is often underestimated and little is known about clinical implications and optimal treatment. Hypermobile persons are often restricted in performing sports or leisure activities, as well as during work, due to pain and disability (1). Adequate muscle strength for movement control might be an important issue to overcome these restrictions. However, little is known about muscle properties of women with GJH. Although it is commonly recognized that strength and muscle cross-sectional area (CSA) are related, the exact relationship seems complex and remains unclear.ObjectivesThe aim of the study was to analyze the correlation between muscle strength and muscle CSA in women with GJH.MethodsThis cross-sectional study included 52 hypermobile women (mean age 26.7±4.7 years, weight 62.4±10.8 kg, BMI 22.8±3.6 kg/m2) with a Beighton-score of six or more (2). Maximum isometric muscle strength for knee extensors and flexors was measured and calculated as maximal voluntary contraction (MVC) and rate of force development (RFD). Muscle CSA of thigh was measured at one third above knee using peripheral quantitative computer tomography (pQCT). Parameters were calculated as absolute values and related to body weight. Correlation coefficients according to Pearson (r) were calculated, as well as the coefficient of determination (r2) in percent. Significance level was set at p=0.05.ResultsFor the absolute values significant correlations were found between MVC and muscle CSA with r=0.46 (r2=21%, p<0.001) for knee extensors and r=0.29 (r2=9%, p=0.035) for flexors. Values related to body weigh showed comparable correlations for MVC and additional significant correlation between RFD of knee extensors and CSA with r=0.31 (r2=9%, p=0.028). Regarding strength, the correlation between MVC and RFD for extensors was significant at a middle level (r=0.52, r2=27%, p<0.001), as well as for flexors (r=0.56, r2=32%, p<0.001). Between flexors and extensors correlations were middle, with r=0.69 (r2=48%, p<0.001) for MVC and r=0.51 (r2=26%, p<0.001) for RFD. Finally, body weight was correlated with muscle CSA (r=0.52, r2=27%, p<0.001), only weak with MVC of extensors (r=0.26, r2=7%, p=0.059), but not with RFD of extensors (r=0.009).ConclusionsMaximum strength of knee extensors and flexors was correlated with muscle CSA of thigh, with values comparable to studies with healthy or exercising people (3). Correlations were highly significant, but on a low level with r2 from 9 to 21%. This indicates that muscle CSA is not solely responsible for the determination of adequate muscle strength. The fact that RFD of knee extensors was only correlated when related to body weight, may point to the importance of fibre type distribution and neuromuscular control (4). In contrast MVC is more dependent on muscle CSA. To conclude, muscle strength is a complex phenomenon, especially RFD and depends on various factors, not solely on muscle CSA.ReferencesSimmonds & Keer, Manual Therapy 2007:298-309.Remvig et al. The Journal of Rheumatology 2007:798-803.Remvig et al. The Journal of Rheumatology 2007:798-803.Jones et al. Sports Med 2008:987-994.Andersen & Aagard, Eur J Appl Physiol 2006:46-52.AcknowledgementsThe study was approved by the Ethics Committee of Canton Bern (222/12).Disclosure of InterestNone declared]]></description><issn>0003-4967</issn><issn>1468-2060</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqVkE1OwzAQhS0EEqVwB0tdB-w4P7ZYoFIBARWBaLu2nHhMU-Wn2IlQd91wAm7Yk5BQkNiyGs2890ZPH0IjSs4pZdGFqiq7hLbUufN8QkMP2kLZc8aYOEADGkS8O0fkEA0IIcwLRBQfoxPnVt1KOOUD1M6TBYl85iXPL7vtx0OdVw1ONmuwZZ3mRd5s8G77iXOH50uwgBWe1NZCoZq8rvA1NO8AFX5sXVYAntjaOTyDrBdVgccWFFaV_tVnjYXqtVlenaIjowoHZz9ziBa3N_NJ4k2f7u4n46mXUj_mHjciDLSJQy1MGKSpUUEW-ZkCbkhqQiM0if2Y-VkqIPNVGHNhDGjdyUaDEWyIRvu_a1u_teAauapb21VzkgpCY95R5J3rcu_K-v4WjFzbvFR2IymRPWf5h7PsOctvzrLn3KWjfTotV_8KfgGx5Yx6</recordid><startdate>201506</startdate><enddate>201506</enddate><creator>Luder, G.</creator><creator>Haehni, M.</creator><creator>Mueller Mebes, C.</creator><creator>Verra, M.L.</creator><creator>Aeberli, D.</creator><creator>Baeyens, J.-P.</creator><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>201506</creationdate><title>THU0623-HPR Joint Hypermobility – is There a Correlation Between Muscle Cross Sectional Area and Muscle Strength?</title><author>Luder, G. ; Haehni, M. ; Mueller Mebes, C. ; Verra, M.L. ; Aeberli, D. ; Baeyens, J.-P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1278-8f954df75d9f54bbfa4c62cae8f0bf5f9d072732cb9ec2a5789ffedd8f0fdef93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Luder, G.</creatorcontrib><creatorcontrib>Haehni, M.</creatorcontrib><creatorcontrib>Mueller Mebes, C.</creatorcontrib><creatorcontrib>Verra, M.L.</creatorcontrib><creatorcontrib>Aeberli, D.</creatorcontrib><creatorcontrib>Baeyens, J.-P.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Annals of the rheumatic diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luder, G.</au><au>Haehni, M.</au><au>Mueller Mebes, C.</au><au>Verra, M.L.</au><au>Aeberli, D.</au><au>Baeyens, J.-P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>THU0623-HPR Joint Hypermobility – is There a Correlation Between Muscle Cross Sectional Area and Muscle Strength?</atitle><jtitle>Annals of the rheumatic diseases</jtitle><date>2015-06</date><risdate>2015</risdate><volume>74</volume><issue>Suppl 2</issue><spage>1316</spage><epage>1317</epage><pages>1316-1317</pages><issn>0003-4967</issn><eissn>1468-2060</eissn><coden>ARDIAO</coden><abstract><![CDATA[BackgroundGeneralized Joint Hypermobility (GJH) is often underestimated and little is known about clinical implications and optimal treatment. Hypermobile persons are often restricted in performing sports or leisure activities, as well as during work, due to pain and disability (1). Adequate muscle strength for movement control might be an important issue to overcome these restrictions. However, little is known about muscle properties of women with GJH. Although it is commonly recognized that strength and muscle cross-sectional area (CSA) are related, the exact relationship seems complex and remains unclear.ObjectivesThe aim of the study was to analyze the correlation between muscle strength and muscle CSA in women with GJH.MethodsThis cross-sectional study included 52 hypermobile women (mean age 26.7±4.7 years, weight 62.4±10.8 kg, BMI 22.8±3.6 kg/m2) with a Beighton-score of six or more (2). Maximum isometric muscle strength for knee extensors and flexors was measured and calculated as maximal voluntary contraction (MVC) and rate of force development (RFD). Muscle CSA of thigh was measured at one third above knee using peripheral quantitative computer tomography (pQCT). Parameters were calculated as absolute values and related to body weight. Correlation coefficients according to Pearson (r) were calculated, as well as the coefficient of determination (r2) in percent. Significance level was set at p=0.05.ResultsFor the absolute values significant correlations were found between MVC and muscle CSA with r=0.46 (r2=21%, p<0.001) for knee extensors and r=0.29 (r2=9%, p=0.035) for flexors. Values related to body weigh showed comparable correlations for MVC and additional significant correlation between RFD of knee extensors and CSA with r=0.31 (r2=9%, p=0.028). Regarding strength, the correlation between MVC and RFD for extensors was significant at a middle level (r=0.52, r2=27%, p<0.001), as well as for flexors (r=0.56, r2=32%, p<0.001). Between flexors and extensors correlations were middle, with r=0.69 (r2=48%, p<0.001) for MVC and r=0.51 (r2=26%, p<0.001) for RFD. Finally, body weight was correlated with muscle CSA (r=0.52, r2=27%, p<0.001), only weak with MVC of extensors (r=0.26, r2=7%, p=0.059), but not with RFD of extensors (r=0.009).ConclusionsMaximum strength of knee extensors and flexors was correlated with muscle CSA of thigh, with values comparable to studies with healthy or exercising people (3). Correlations were highly significant, but on a low level with r2 from 9 to 21%. This indicates that muscle CSA is not solely responsible for the determination of adequate muscle strength. The fact that RFD of knee extensors was only correlated when related to body weight, may point to the importance of fibre type distribution and neuromuscular control (4). In contrast MVC is more dependent on muscle CSA. To conclude, muscle strength is a complex phenomenon, especially RFD and depends on various factors, not solely on muscle CSA.ReferencesSimmonds & Keer, Manual Therapy 2007:298-309.Remvig et al. The Journal of Rheumatology 2007:798-803.Remvig et al. The Journal of Rheumatology 2007:798-803.Jones et al. Sports Med 2008:987-994.Andersen & Aagard, Eur J Appl Physiol 2006:46-52.AcknowledgementsThe study was approved by the Ethics Committee of Canton Bern (222/12).Disclosure of InterestNone declared]]></abstract><cop>Kidlington</cop><pub>Elsevier Limited</pub><doi>10.1136/annrheumdis-2015-eular.3339</doi><tpages>2</tpages></addata></record> |
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| title | THU0623-HPR Joint Hypermobility – is There a Correlation Between Muscle Cross Sectional Area and Muscle Strength? |
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