Design, Synthesis, and Antiviral Activity of Novel Chalcone Derivatives Containing a Purine Moiety

To find new antiviral agents,novel chalcone derivatives containing a purine moiety were designed and synthesized by combining bioactive substructures.The antiviral activities of the derivatives against tobacco mosaic virus （TMV） and cucumber mosaic virus （CMV） were evaluated.Results showed that most...

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Veröffentlicht in:	Chinese journal of chemistry 2017-05, Vol.35 (5), p.665-672
Hauptverfasser:	Gan, Xiuhai, Wang, Yanjiao, Hu, Deyu, Song, Baoan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral activity Antiviral agents Biocompatibility chalcone Coat protein cucumber mosaic virus Deactivation Derivatives Design Inactivation purine Ribavirin Substructures Tobacco tobacco mosaic virus Viruses
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