Pharmacokinetics and relative bioavailability of two allopurinol tablets in healthy Chinese volunteers

To evaluate the pharmacokinetics and relative bioavailability of two allopurinol tablets in healthy Chinese volunteers. A single-center, randomized, cross-over, two-period study design was conducted in healthy male subjects who were identified as not carrying the HLA-B*58:01 allele. Under fasting co...

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Veröffentlicht in:	International journal of clinical pharmacology and therapeutics 2017-06, Vol.55 (6), p.540-546
Hauptverfasser:	Hou, Zhen-Yan, Cai, Hua-Lin, Deng, Yang, Li, Zhi-Hua, Cao, Si-Si, Chen, Ying, Li, Yao, Yan, Miao, Zhang, Bi-Kui
Format:	Artikel
Sprache:	eng
Schlagworte:	Allopurinol - adverse effects Allopurinol - pharmacokinetics Area Under Curve Bioavailability Biological Availability Chromatography, High Pressure Liquid Cross-Over Studies Humans Male Pharmacokinetics Tablets
Online-Zugang:	Volltext
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