Hypothyroidism reduces mammary tumor progression via [Beta]-catenin-activated intrinsic apoptotic pathway in rats

Experimental hypothyroidism retards mammary carcinogenesis promoting apoptosis of tumor cells. [beta]-catenin plays a critical role in cell adhesion and intracellular signaling pathways conditioning the prognosis of breast cancer. However, the mechanistic connections associated with the expression o...

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Veröffentlicht in:	Histochemistry and cell biology 2017-06, Vol.147 (6), p.759
Hauptverfasser:	López Fontana, C M, Zyla, L E, Santiano, F E, Sasso, C V, Cuello-carrión, F D, Pistone Creydt, V, Fanelli, M A, Carón, R W
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Anthracene Apoptosis Breast cancer Carcinogenesis Caspase Caspase-3 Caspase-9 Cell adhesion Cell adhesion & migration Drinking water Hypothyroidism Intracellular signalling Latency Localization Mammary gland Rodents Survivin Thyroid cancer Tumor cells Tumors β-Catenin
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