Haematopoietic induction and hepatic protective roles of Hepacare® in CCl4-induced hepatic damaged rats

Haematopoietic induction and hepatic protective roles of Hepacare® in CCl4-induced hepatic damaged rats

Herbal formulations are plant parts used as raw materials for self-administered pharmaceutical remedies, and many of them are being sold without any scientific validation for their potency and efficacy. This research work was aimed at evaluating the haematopoietic, biochemical, and histological effe...

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Veröffentlicht in:Comparative clinical pathology 2017-05, Vol.26 (3), p.679-688
Hauptverfasser: Adebayo, Abiodun Humphrey, Yakubu, Omolara Faith, Adegbite, Oluwatobi Samuel, Okubena, Olajuwon
Format: Artikel
Sprache:eng
Schlagworte:
Alanine
Alanine transaminase
Alkaline phosphatase
Aspartate aminotransferase
Bilirubin
Carbon tetrachloride
Cell size
Enzymes
Erythrocytes
Hematology
Hemoglobin
Liver
Medicine
Medicine & Public Health
Oncology
Original Article
Oxidative stress
Pathology
Rodents
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Beschreibung
Zusammenfassung:Herbal formulations are plant parts used as raw materials for self-administered pharmaceutical remedies, and many of them are being sold without any scientific validation for their potency and efficacy. This research work was aimed at evaluating the haematopoietic, biochemical, and histological effects of Hepacare®, a popularly sold herbal formulation in Nigeria against carbon tetrachloride (CCl 4 )-mediated liver damage in rats. Haematological analysis showed significant reduction ( p  
ISSN:1618-5641
1618-565X
DOI:10.1007/s00580-017-2428-0