The Use of Cyclosporine A in Rheumatology: a 2016 Comprehensive Review

Cyclosporine A, an inhibitor of calcineurin, exerts an immunomodulator action interfering with T cell activation. Even though novel therapeutic tools have emerged, CyA still represents a suitable option in several clinical rheumatology settings. This is the case of refractory nephritis and cytopenia...

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Veröffentlicht in:	Clinical reviews in allergy & immunology 2017-06, Vol.52 (3), p.401-423
Hauptverfasser:	Chighizola, Cecilia Beatrice, Ong, Voon H., Meroni, Pier Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Adult Allergology Arthritis Arthritis, Juvenile - drug therapy Behcet Syndrome - drug therapy Child Chronic conditions Cyclosporine - therapeutic use Gestation Health aspects Hepacivirus - physiology Hepatitis C Hepatitis C, Chronic - drug therapy Humans Immunology Immunomodulators Immunosuppressive Agents - therapeutic use Interferon Internal Medicine Lupus Lupus Erythematosus, Systemic - drug therapy Lymphocyte Activation - drug effects Lymphocytes Lymphocytes T Macrophages Medicine Medicine & Public Health Nephritis Psoriatic arthritis Refractory materials Rheumatology Rheumatology - trends Sjogren's syndrome Sjogren's Syndrome - drug therapy Skin diseases Still's Disease, Adult-Onset - drug therapy Systemic lupus erythematosus T cells T-Lymphocytes - drug effects T-Lymphocytes - immunology Virus Replication
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