D-[beta]-aspartyl residue exhibiting uncommon high resistance to spontaneous peptide bond cleavage

Although L-amino acids were selected as main constituents of peptides and proteins during chemical evolution, D-aspartyl (Asp) residue is found in a variety of living tissues. In particular, D-β-Asp is thought to be stable than any other Asp isomers, and this could be a reason for gradual accumulati...

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Veröffentlicht in:	Scientific reports 2016-02, Vol.6, p.21594
Hauptverfasser:	Aki, Kenzo, Okamura, Emiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Conformation Crystallin Eye lens Isomers NMR Nuclear magnetic resonance Peptides
Online-Zugang:	Volltext
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