Non-tumor tissue derived interleukin-17B activates IL-17RB/AKT/[beta]-catenin pathway to enhance the stemness of gastric cancer

Inflammation is a critical component involved in tumor progression. Interleukin-17 (IL-17) belongs to a relatively new family of cytokines that has been associated with the progression of cancers. However, the role of IL-17B/IL-17RB (IL-17 receptor B) signaling to stemness of gastric cancer remains...

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Veröffentlicht in:	Scientific reports 2016-05, Vol.6, p.25447
Hauptverfasser:	Bie, Qingli, Sun, Caixia, Gong, Aihua, Li, Chunye, Su, Zhaoliang, Zheng, Dong, Ji, Xiaoyun, Wu, Yumin, Guo, Qi, Wang, Shengjun, Xu, Huaxi
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Cytokines Gastric cancer Interleukin 17 Nuclear transport Translocation Tumor cells Tumors β-Catenin
Online-Zugang:	Volltext
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