A Novel Scale Linking Potency and Dosage to Estimate Anticholinergic Exposure in Older Adults: the Muscarinic Acetylcholinergic Receptor ANTagonist Exposure Scale

Quantification of the anticholinergic exposure insufficiently or imprecisely incorporates dosage information, leading to inaccurate estimations. The aim was to construct a novel scale, including potency and dosage for the quantification of the anticholinergic exposure in older adults. Potency inform...

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Veröffentlicht in:	Basic & clinical pharmacology & toxicology 2017-06, Vol.120 (6), p.582-590
Hauptverfasser:	Klamer, Therese T., Wauters, Maarten, Azermai, Majda, Durán, Carlos, Christiaens, Thierry, Elseviers, Monique, Vander Stichele, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors Acetylcholine receptors (muscarinic) Adults Aged Anticholinergics Citalopram Cohort Studies Communities Data acquisition Dosage Drug Utilization Exposure Feedback Humans Information retrieval Maintenance Muscarinic Antagonists - administration & dosage Muscarinic Antagonists - therapeutic use Nursing homes Older people Reviews
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