Lewis Acid Promoted Single C–F Bond Activation of the CF3 Group: SN1′‐Type 3,3‐Difluoroallylation of Arenes with 2‐Trifluoromethyl‐1‐alkenes

Activation of the sp3 C−F bond in 2‐trifluoromethyl‐1‐alkenes was accomplished through treatment with a Lewis acid. In the presence of an equimolar amount of EtAlCl2, the (trifluoromethyl)alkenes readily underwent an SN1′‐type reaction with arenes through a Friedel–Crafts‐type mechanism via eliminat...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie International Edition 2017-05, Vol.56 (21), p.5890-5893
Hauptverfasser:	Fuchibe, Kohei, Hatta, Hibiki, Oh, Ken, Oki, Rie, Ichikawa, Junji
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Alkenes allylation Aromatic compounds carbocations C−F bond activation Fluorides fluorine Lewis acid Lewis acids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!