Improved Laboratory Synthesis of YC-071, a Potent Azole Antifungal Agent

An improved laboratory synthesis of YC-071, a potent azole antifungal agent, has been developed. Compared with the original route, the new route is operationally simple, requiring only limited purification of all the intermediates. The new route is an important scalable synthesis, which meets the ne...

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Veröffentlicht in:	Journal of chemical research 2017-04, Vol.41 (4), p.241-245
Hauptverfasser:	Zheng, Yazhou, Qian, Anran, Ling, Chenyu, Cao, Xufeng, Cui, YongMei, Yang, Yushe
Format:	Artikel
Sprache:	eng
Schlagworte:	Azoles Chemical synthesis Fungicides Heterocyclic compounds Purification
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