Synthesis, docking, and evaluation of novel thiazoles for potent antidiabetic activity

In this study, a series of novel substituted pyrazoles containing indole and thiazole motifs were synthesized and evaluated for their antihyperglycemic activity against α -amylase and α -glucosidase enzymes. Among them, 2-(5-(1 H -indol-3-yl)-3-phenyl-1 H -pyrazol-1-yl)-4-(4-bromo phenyl) thiazole (...

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