FTO is required for myogenesis by positively regulating mTOR-PGC-1[alpha] pathway-mediated mitochondria biogenesis

Global germ line loss of fat mass- and obesity-associated (FTO) gene results in both the reduction of fat mass and lean mass in mice. The role of FTO in adipogenesis has been proposed, however, that in myogenesis has not. Skeletal muscle is the main component of body lean mass, so its connection wit...

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Veröffentlicht in:	Cell death & disease 2017-03, Vol.8 (3)
Hauptverfasser:	Wang, Xiaobo, Huang, Ning, Yang, Min, Wei, Dandan, Tai, Haoran, Han, Xiaojuan, Gong, Hui, Zhou, Jiao, Qin, Jianqiong, Wei, Xiawei, Chen, Honghan, Fang, Tingting, Xiao, Hengyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Mitochondria Myogenesis
Online-Zugang:	Volltext
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