Synthesis of novel 4-hydroxycarbazole derivatives and evaluation of their in vitro anti-inflammatory, anti-oxidant activities and molecular docking

Synthesis of novel 4-hydroxycarbazole derivatives 4a – q has been reported in good yields. The reaction involves O -alkylation of 4-hydroxycarbazole using methyl 5-bromovalerate results in 2 , which on hydrolysis followed by coupling reaction with different primary and secondary amines leads to the...

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Veröffentlicht in:Research on chemical intermediates 2017-05, Vol.43 (5), p.3377-3393
Hauptverfasser: Muniyappan, Govindhan, Kathvarayan, Subramanian, Kella, Chennakesava Rao, Kalliyappan, Easwaramoorthi, Ponnusamy, Senthilkumar, Thirumalai, Perumal P.
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Sprache:eng
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