Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3Beta/Beta-catenin pathways

Background Metastasis is a major cause of death in human colorectal cancer patients. However, the contribution of chemokines in the tumor microenvironment to tumor metastasis is not fully understood. Methods Herein, we examinined several chemokines in colorectal cancer patients using chemokine ELISA...

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Veröffentlicht in:	Molecular cancer 2017-01, Vol.16
Hauptverfasser:	Ou, Jingkun Zhaoochi, Han, Dingpei, Wang, Puxiongzhi, Zong, Yaping, Zhu, Congcong, Liu, Di, Zheng, Minhua, Sun, Jing, Feng, Hao, Lu, Aiguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Activation Animal tissues Chemokines Colorectal cancer Colorectal carcinoma Elk Immunofluorescence Liver Medical prognosis Membranes Metastasis Mice Migration Molecular biology Patients Promoters Proteins Rodents Tissues
Online-Zugang:	Volltext
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