Decreasing Risk of Leukemia with Prolonged Follow-up after Chemotherapy and Radiotherapy for Hodgkin's Disease

Acute nonlymphocytic leukemia is a recognized complication of combined chemotherapy and radiation treatment of patients with Hodgkin's disease. Previous studies have suggested that the risk of leukemia in these patients increases with time after treatment. We analyzed the occurrence of second n...

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Veröffentlicht in:	The New England journal of medicine 1987-03, Vol.316 (12), p.710-714
Hauptverfasser:	Blayney, Douglas W, Longo, Dan L, Young, Robert C, Greene, Mark H, Hubbard, Susan M, Postal, Marcia G, Duffey, Patricia L, DeVita, Vincent T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences Bone marrow Bone Marrow - pathology Cancer therapies Chemotherapy Combined Modality Therapy Female Hematologic and hematopoietic diseases Hodgkin Disease - therapy Humans Leukemia Leukemia - epidemiology Leukemia - etiology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Mechlorethamine - adverse effects Medical sciences Middle Aged Myelodysplastic Syndromes - etiology Neoplasms, Multiple Primary Patients Prednisone - adverse effects Procarbazine - adverse effects Radiation therapy Radiotherapy - adverse effects Risk Time Factors Vincristine - adverse effects
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