3D-QSAR studies on lipid peroxidation inhibitory activity of chromone derivatives

Lipid peroxidation has been implicated in disease states such as atherosclerosis, asthma, neurodegenerative disorders, Parkinson’s disease, cancer, etc. In this study, the anti-lipid peroxidation activity for a series of chromone compounds, evaluated in vitro by ferric thiocyanate and thiobarbituric...

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Veröffentlicht in:	Medicinal chemistry research 2016-10, Vol.25 (10), p.2368-2379
Hauptverfasser:	Phosrithong, Narumol, Ungwitayatorn, Jiraporn
Format:	Artikel
Sprache:	eng
Schlagworte:	Arteriosclerosis Assaying Asthma Atherosclerosis Biochemistry Biomedical and Life Sciences Biomedicine Catechol Cell Biology Ferric thiocyanate Lipid peroxidation Lipids Molecular modelling Molecular structure Movement disorders Neurodegenerative diseases Original Research Parkinson's disease Pharmacology/Toxicology Similarity Structure-activity relationships Thiobarbituric acid Thiocyanates
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