In silico investigation of morpholines as novel class of trypanosomal triosephosphate isomerase inhibitors

Human African trypanosomiasis, also known as sleeping sickness , is caused by the single-celled kinetoplastid parasite Trypanosoma brucei transmitted to humans by infected tsetse flies. The disease threatens millions of people. Currently available treatment options are faced with some important chal...

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Veröffentlicht in:Medicinal chemistry research 2017, Vol.26 (1), p.180-189
Hauptverfasser: Ibezim, Akachukwu, Nwodo, Ngozi Justina, Nnaji, Nnaemeka J.N., Ujam, Oguejiofo T., Olubiyi, Olujide O., Mba, Chika J.
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