6,7‐Dimethoxy‐quinazolin‐4‐yl‐amino‐thiophene‐2‐carboxamides as Potent Inhibitors of VEGF Receptors 1 and 2

The identification of agents with antiproliferative activity against endothelial cells has significant value for the treatment of many angiogenesis‐dependent pathologies. The vascular endothelial growth factor (VEGF) and its receptors have been implicated as key factors in tumor angiogenesis and are...

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Veröffentlicht in:Journal of heterocyclic chemistry 2017-03, Vol.54 (2), p.1065-1070
Hauptverfasser: Ashok, Abhishek, Thanukrishnan, Kannan, Bhojya Naik, Halehatty S., Shaik, Abdul Gaffar
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Sprache:eng
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