Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-[kappa]B

Exposure of endothelial cells to low and multidirectional blood flow is known to promote a pro-atherogenic phenotype. The mechanics of the vessel wall is another important mechano-stimulus within the endothelial cell environment, but no study has examined whether changes in the magnitude and directi...

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Veröffentlicht in:Annals of biomedical engineering 2017-04, Vol.45 (4), p.898
Hauptverfasser: Pedrigi, Ryan M, Papadimitriou, Konstantinos I, Kondiboyina, Avinash, Sidhu, Sukhjinder, Chau, James, Patel, Miten B, Baeriswyl, Daniel C, Drakakis, Emmanuel M, Krams, Rob
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