Risks of Anticoagulant Therapy in Pregnant Women with Artificial Heart Valves

In an attempt to identify the best treatment for pregnant women with cardiac-valve prostheses who are receiving oral anticoagulants, we studied 72 pregnancies prospectively. In 23 pregnancies (Group I), the coumarin derivative acenocoumarol was discontinued and the patients received 5000 U of subcut...

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Veröffentlicht in:	The New England journal of medicine 1986-11, Vol.315 (22), p.1390-1393
Hauptverfasser:	Iturbe-Alessio, Ignacio, Fonseca, María del Carmen, Mutchinik, Osvaldo, Santos, Miguel Angel, Zajarías, Alejandro, Salazar, Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - etiology Abortion Abortion, Spontaneous - chemically induced Acenocoumarol - administration & dosage Acenocoumarol - adverse effects Adolescent Adult Anticoagulants Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cardiac arrhythmia Coagulation Coumarin Coumarins - administration & dosage Coumarins - adverse effects Drug Administration Schedule Female Fetal Death - chemically induced Fetus - drug effects Fetuses Gestation Health risk assessment Heart Heart diseases Heart Valve Prosthesis Heparin Heparin - administration & dosage Heparin - adverse effects Humans Infant, Newborn Medical sciences Patients Pharmacology. Drug treatments Pregnancy Pregnancy Complications, Cardiovascular - prevention & control Pregnancy Trimester, First Prostheses Prosthetic valves Prosthetics Thromboembolism Thromboembolism - prevention & control Thrombosis
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