Anthelmintic Actions of the Cyclic Depsipeptide PF1022A and its Electrophysiological Effects on Muscle Cells of Ascaris suum

The cyclic depsipeptide PF1022A, given orally to mice, showed very good anthelmintic activity against Heligmosomoides polygyrus and Heterakis spumosa at 50 mg kg−1. In vitro, PF1022A was very active against Trichinella spiralis and had good activity against Nippostrongylus brasiliensis at 1 μg ml−1....

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Veröffentlicht in:	Pesticide Science 1996-12, Vol.48 (4), p.343-349
Hauptverfasser:	Martin, Richard J., Harder, Achim, Londershausen, Michael, Jeschke, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	anthelmintic Ascaris suum cyclic depsipeptide electrophysiology Heligmosomoides polygyrus Heterakis spumosa mode of action mouse PF1022A
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