Genetic effects of phthalimide fungicides on diploid Aspergillus nidulans
A few specimens of ‘Ridomil 25 WP’, a commercial formulation of metalaxyl, showed high genetic activity on a heterozygous diploid strain of Aspergillus nidulans. This activity was due to an impurity which was identified by mass and n.m.r. spectroscopy as captafol. This and the related fungicides cap...
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Veröffentlicht in: | Pesticide Science 1987, Vol.20 (3), p.193-205 |
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description | A few specimens of ‘Ridomil 25 WP’, a commercial formulation of metalaxyl, showed high genetic activity on a heterozygous diploid strain of Aspergillus nidulans. This activity was due to an impurity which was identified by mass and n.m.r. spectroscopy as captafol. This and the related fungicides captan, dichlofluanid, and tolyfluanid greatly increased the yield of euploid colour segregants from the diploid strain. At low captafol concentrations, most of the induced segregants resulted from mitotic crossing over but chromosome non‐disjunction or loss was also caused at high concentrations. Mitotic crossing over could be induced also by vapour‐phase action of captafol and captan. The mechanism by which these phthalimides may exert their genetic effects is discussed. |
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This activity was due to an impurity which was identified by mass and n.m.r. spectroscopy as captafol. This and the related fungicides captan, dichlofluanid, and tolyfluanid greatly increased the yield of euploid colour segregants from the diploid strain. At low captafol concentrations, most of the induced segregants resulted from mitotic crossing over but chromosome non‐disjunction or loss was also caused at high concentrations. Mitotic crossing over could be induced also by vapour‐phase action of captafol and captan. The mechanism by which these phthalimides may exert their genetic effects is discussed.</description><identifier>ISSN: 0031-613X</identifier><identifier>ISSN: 1526-498X</identifier><identifier>EISSN: 1096-9063</identifier><identifier>DOI: 10.1002/ps.2780200305</identifier><identifier>CODEN: PSSCBG</identifier><language>eng</language><publisher>London: John Wiley & Sons, Ltd</publisher><subject>Aspergillus nidulellus ; Biological and medical sciences ; captafol ; Chemical control ; Control ; Fundamental and applied biological sciences. Psychology ; Fungal plant pathogens ; genetic control ; metalaxyl ; Phytopathology. Animal pests. Plant and forest protection</subject><ispartof>Pesticide Science, 1987, Vol.20 (3), p.193-205</ispartof><rights>Copyright © 1987 John Wiley & Sons, Ltd</rights><rights>1989 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4045-518fc49ba6040bd58b4ce44c04b2fb356ba1368d6b6e9a44050e419203e31a93</citedby><cites>FETCH-LOGICAL-c4045-518fc49ba6040bd58b4ce44c04b2fb356ba1368d6b6e9a44050e419203e31a93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fps.2780200305$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fps.2780200305$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,4024,27869,27923,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=7013352$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Ziogas, B.N</creatorcontrib><creatorcontrib>Georgopoulos, S.G</creatorcontrib><title>Genetic effects of phthalimide fungicides on diploid Aspergillus nidulans</title><title>Pesticide Science</title><addtitle>Pestic. Sci</addtitle><description>A few specimens of ‘Ridomil 25 WP’, a commercial formulation of metalaxyl, showed high genetic activity on a heterozygous diploid strain of Aspergillus nidulans. This activity was due to an impurity which was identified by mass and n.m.r. spectroscopy as captafol. This and the related fungicides captan, dichlofluanid, and tolyfluanid greatly increased the yield of euploid colour segregants from the diploid strain. At low captafol concentrations, most of the induced segregants resulted from mitotic crossing over but chromosome non‐disjunction or loss was also caused at high concentrations. Mitotic crossing over could be induced also by vapour‐phase action of captafol and captan. The mechanism by which these phthalimides may exert their genetic effects is discussed.</description><subject>Aspergillus nidulellus</subject><subject>Biological and medical sciences</subject><subject>captafol</subject><subject>Chemical control</subject><subject>Control</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fungal plant pathogens</subject><subject>genetic control</subject><subject>metalaxyl</subject><subject>Phytopathology. Animal pests. 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Psychology</topic><topic>Fungal plant pathogens</topic><topic>genetic control</topic><topic>metalaxyl</topic><topic>Phytopathology. Animal pests. 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subjects | Aspergillus nidulellus Biological and medical sciences captafol Chemical control Control Fundamental and applied biological sciences. Psychology Fungal plant pathogens genetic control metalaxyl Phytopathology. Animal pests. Plant and forest protection |
title | Genetic effects of phthalimide fungicides on diploid Aspergillus nidulans |
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