Back Cover: Alcohol‐Enhanced Cu‐Mediated Radiofluorination (Chem. Eur. J. 14/2017)
Alcohol is the solution: The potential of many 18F‐labeled (hetero)aromatics for positron emission tomography (PET) remains underexploited, so the development and optimization of radiolabeling procedures remains a research area of considerable interest. It is shown herein that alcohol‐containing sol...
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| Veröffentlicht in: | Chemistry : a European journal 2017-03, Vol.23 (14), p.3498-3498 |
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| container_issue | 14 |
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| container_title | Chemistry : a European journal |
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| creator | Zischler, Johannes Kolks, Niklas Modemann, Daniel Neumaier, Bernd Zlatopolskiy, Boris D. |
| description | Alcohol is the solution: The potential of many 18F‐labeled (hetero)aromatics for positron emission tomography (PET) remains underexploited, so the development and optimization of radiolabeling procedures remains a research area of considerable interest. It is shown herein that alcohol‐containing solvent systems give rise to unexpectedly enhanced copper‐mediated aromatic 18F‐labeling, enabling rapid radiolabeling of a broad scope of boronic and stannyl substrates under general reaction conditions. Among others, this allows the direct synthesis of radiofluorinated indoles, phenols, and anilines from unprotected precursors. More information can be found in the Communication by B. Neumaier et al. on page 3251 ff. |
| doi_str_mv | 10.1002/chem.201700191 |
| format | Article |
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| language | eng |
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| subjects | Alcohol Chemistry copper fluorination imaging agents positron emission tomography radiopharmaceuticals |
| title | Back Cover: Alcohol‐Enhanced Cu‐Mediated Radiofluorination (Chem. Eur. J. 14/2017) |
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