Can body composition be used to optimize the dose of platinum chemotherapy in lung cancer? A feasibility study

Purpose Current methods of dosing platinum-based chemotherapy are suboptimal. Potentially, taking lean body mass into account may help. To inform the design of a future study, we first examined the feasibility and acceptability of such an approach using dual-energy X-ray absorptiometry (DEXA) and ex...

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Veröffentlicht in:	Supportive care in cancer 2017-04, Vol.25 (4), p.1257-1261
Hauptverfasser:	Crosby, Vincent, D’Souza, Catherine, Bristow, Carina, Proffitt, Amy, Hussain, Asmah, Potter, Vanessa, Hennig, Ivo, O’Connor, Richard, Baracos, Vickie, Wilcock, Andrew
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - pharmacology Antineoplastic Combined Chemotherapy Protocols - therapeutic use Body composition Body Composition - physiology Cancer Carboplatin Chemotherapy Feasibility Studies Female Humans Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - pathology Male Medicine Medicine & Public Health Middle Aged Nursing Nursing Research Oncology Oncology, Experimental Original Article Pain Medicine Pharmacology Physiological aspects Platinum Platinum - administration & dosage Platinum - pharmacology Platinum - therapeutic use Rehabilitation Medicine Toxicity
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