Biotin decorated PLGA nanoparticles containing SN-38 designed for cancer therapy

Active targeted chemotherapy is expected to provide more specific delivery of cytotoxic drugs to the tumor cells and hence reducing the side effects on healthy tissues. Due to the over expression of biotin receptors on cancerous cells as a result of further requirement for rapid proliferations, biot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Artificial cells, nanomedicine, and biotechnology nanomedicine, and biotechnology, 2017-04, Vol.45 (3), p.495-504
Hauptverfasser:	Mehdizadeh, Mozhdeh, Rouhani, Hasti, Sepehri, Nima, Varshochian, Reyhaneh, Ghahremani, Mohammad Hossein, Amini, Mohsen, Gharghabi, Mehdi, Ostad, Seyed Nasser, Atyabi, Fatemeh, Baharian, Azin, Dinarvand, Rassoul
Format:	Artikel
Sprache:	eng
Schlagworte:	Active targeted anti-cancer Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - pharmacology Biological Transport Biotin - chemistry Biotin - metabolism Camptothecin - analogs & derivatives Camptothecin - chemistry Camptothecin - pharmacology Cancer Cancer therapies Cell Survival - drug effects cytotoxic Cytotoxicity Drug Carriers Drug Compounding Drug Liberation Female Humans Hydrogen-Ion Concentration in vitro Kinetics Lactic Acid - chemistry Lactic Acid - metabolism MCF-7 Cells Nanoparticles Nanoparticles - chemistry Nanoparticles - ultrastructure Particle Size Polyethylene Glycols - chemistry Polyglycolic Acid - chemistry Polyglycolic Acid - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!