Formal Enantioselective Hydroamination of Non‐Activated Alkenes: Transformation of Styrenes into Enantiomerically Pure 1‐Phenylethylamines in Chemoenzymatic One‐Pot Synthesis

As a complementary approach to current asymmetric synthetic methods, a direct transformation of styrenes into 1‐phenylethylamines was developed. The one‐pot process represents a formal hydroamination of a non‐activated alkene with ammonia and is based on the combination of a Pd/Cu‐catalyzed Wacker‐o...

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Veröffentlicht in:	ChemCatChem 2017-02, Vol.9 (4), p.555-558
Hauptverfasser:	Uthoff, Florian, Sato, Hirofumi, Gröger, Harald
Format:	Artikel
Sprache:	eng
Schlagworte:	amines asymmetric synthesis compartmentation hydroamination transamination
Online-Zugang:	Volltext
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