Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial
Rationale Loss of smell is a major consequence for chronic sinusitis patients with nasal polyps and is a severity marker with significant impact on quality of life.
Gespeichert in:
Veröffentlicht in: | Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB90-AB90 |
---|---|
Hauptverfasser: | , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | AB90 |
---|---|
container_issue | 2 |
container_start_page | AB90 |
container_title | Journal of allergy and clinical immunology |
container_volume | 139 |
creator | Naclerio, Robert M., MD, FAAAAI Hamilos, Daniel L., MD, FAAAAI Ferguson, Berrylin J., MD Bachert, Claus, MD, PhD Hellings, Peter W., MD, PhD Mullol, Joaquim, MD, PhD, FAAAAI Gevaert, Philippe, MD Zhang, Donghui Khan, Asif Fan, Chunpeng Joish, Vijay N Amin, Nikhil Pirozzi, Gianluca Graham, Neil MH Staudinger, Heribert W., MD Grabher, Annette Mannent, Leda |
description | Rationale Loss of smell is a major consequence for chronic sinusitis patients with nasal polyps and is a severity marker with significant impact on quality of life. |
doi_str_mv | 10.1016/j.jaci.2016.12.245 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1867963805</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0091674916317638</els_id><sourcerecordid>4313589641</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2285-d1b9aea1285e69eef9817d21c77d6b796b060680bf274f8ed6f7ceecfb6d210b3</originalsourceid><addsrcrecordid>eNp9kd2O0zAQhS0EEmXhBbiyxHWC7bR2ghBS1eVnpRVUdLm2HGdMHZy4eJJFfQmeGYciIXHBlcfyOTPH3xDynLOSMy5f9mVvrC9FrksuSrHePCArzhpVyFpsHpIVYw0vpFo3j8kTxJ7le1U3K_Lzej75MA-mpTfDKcV7QHqAEYFGRw8DhEDN2NHP0M02P23HiIM3dDvE8Svdm8nDOCH94acj_WjQBLqP4XyK6PG3b3dMcfSWHvw4o588vsqtcA7Z41IcqKH7o8nDhKF3yZvwlDxyJiA8-3NekS_v3t7tPhS3n97f7La3hRWi3hQdbxsDhucaZAPgmpqrTnCrVCdb1ciWSSZr1jqh1q6GTjplAaxrZVaxtroiLy5985e_z4CT7uOcxjxS81rmBlXNNlklLiqbImICp0_JDyadNWd64a57vXDXC3fNhc7cs-n1xQQ5_72HpNFmShY6n8BOuov-__Y3_9ht8BmhCd_gDPg3pkahmT4si132ymXFVY5d_QLLX6IO</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1867963805</pqid></control><display><type>article</type><title>Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial</title><source>ScienceDirect Journals (5 years ago - present)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Naclerio, Robert M., MD, FAAAAI ; Hamilos, Daniel L., MD, FAAAAI ; Ferguson, Berrylin J., MD ; Bachert, Claus, MD, PhD ; Hellings, Peter W., MD, PhD ; Mullol, Joaquim, MD, PhD, FAAAAI ; Gevaert, Philippe, MD ; Zhang, Donghui ; Khan, Asif ; Fan, Chunpeng ; Joish, Vijay N ; Amin, Nikhil ; Pirozzi, Gianluca ; Graham, Neil MH ; Staudinger, Heribert W., MD ; Grabher, Annette ; Mannent, Leda</creator><creatorcontrib>Naclerio, Robert M., MD, FAAAAI ; Hamilos, Daniel L., MD, FAAAAI ; Ferguson, Berrylin J., MD ; Bachert, Claus, MD, PhD ; Hellings, Peter W., MD, PhD ; Mullol, Joaquim, MD, PhD, FAAAAI ; Gevaert, Philippe, MD ; Zhang, Donghui ; Khan, Asif ; Fan, Chunpeng ; Joish, Vijay N ; Amin, Nikhil ; Pirozzi, Gianluca ; Graham, Neil MH ; Staudinger, Heribert W., MD ; Grabher, Annette ; Mannent, Leda</creatorcontrib><description>Rationale Loss of smell is a major consequence for chronic sinusitis patients with nasal polyps and is a severity marker with significant impact on quality of life.</description><identifier>ISSN: 0091-6749</identifier><identifier>EISSN: 1097-6825</identifier><identifier>DOI: 10.1016/j.jaci.2016.12.245</identifier><language>eng</language><publisher>St. Louis: Elsevier Inc</publisher><subject>Allergies ; Allergy and Immunology ; Nose ; Patient assessment</subject><ispartof>Journal of allergy and clinical immunology, 2017-02, Vol.139 (2), p.AB90-AB90</ispartof><rights>2016</rights><rights>Copyright Elsevier Limited Feb 01, 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2285-d1b9aea1285e69eef9817d21c77d6b796b060680bf274f8ed6f7ceecfb6d210b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jaci.2016.12.245$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27922,27923,45993</link.rule.ids></links><search><creatorcontrib>Naclerio, Robert M., MD, FAAAAI</creatorcontrib><creatorcontrib>Hamilos, Daniel L., MD, FAAAAI</creatorcontrib><creatorcontrib>Ferguson, Berrylin J., MD</creatorcontrib><creatorcontrib>Bachert, Claus, MD, PhD</creatorcontrib><creatorcontrib>Hellings, Peter W., MD, PhD</creatorcontrib><creatorcontrib>Mullol, Joaquim, MD, PhD, FAAAAI</creatorcontrib><creatorcontrib>Gevaert, Philippe, MD</creatorcontrib><creatorcontrib>Zhang, Donghui</creatorcontrib><creatorcontrib>Khan, Asif</creatorcontrib><creatorcontrib>Fan, Chunpeng</creatorcontrib><creatorcontrib>Joish, Vijay N</creatorcontrib><creatorcontrib>Amin, Nikhil</creatorcontrib><creatorcontrib>Pirozzi, Gianluca</creatorcontrib><creatorcontrib>Graham, Neil MH</creatorcontrib><creatorcontrib>Staudinger, Heribert W., MD</creatorcontrib><creatorcontrib>Grabher, Annette</creatorcontrib><creatorcontrib>Mannent, Leda</creatorcontrib><title>Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial</title><title>Journal of allergy and clinical immunology</title><description>Rationale Loss of smell is a major consequence for chronic sinusitis patients with nasal polyps and is a severity marker with significant impact on quality of life.</description><subject>Allergies</subject><subject>Allergy and Immunology</subject><subject>Nose</subject><subject>Patient assessment</subject><issn>0091-6749</issn><issn>1097-6825</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNp9kd2O0zAQhS0EEmXhBbiyxHWC7bR2ghBS1eVnpRVUdLm2HGdMHZy4eJJFfQmeGYciIXHBlcfyOTPH3xDynLOSMy5f9mVvrC9FrksuSrHePCArzhpVyFpsHpIVYw0vpFo3j8kTxJ7le1U3K_Lzej75MA-mpTfDKcV7QHqAEYFGRw8DhEDN2NHP0M02P23HiIM3dDvE8Svdm8nDOCH94acj_WjQBLqP4XyK6PG3b3dMcfSWHvw4o588vsqtcA7Z41IcqKH7o8nDhKF3yZvwlDxyJiA8-3NekS_v3t7tPhS3n97f7La3hRWi3hQdbxsDhucaZAPgmpqrTnCrVCdb1ciWSSZr1jqh1q6GTjplAaxrZVaxtroiLy5985e_z4CT7uOcxjxS81rmBlXNNlklLiqbImICp0_JDyadNWd64a57vXDXC3fNhc7cs-n1xQQ5_72HpNFmShY6n8BOuov-__Y3_9ht8BmhCd_gDPg3pkahmT4si132ymXFVY5d_QLLX6IO</recordid><startdate>20170201</startdate><enddate>20170201</enddate><creator>Naclerio, Robert M., MD, FAAAAI</creator><creator>Hamilos, Daniel L., MD, FAAAAI</creator><creator>Ferguson, Berrylin J., MD</creator><creator>Bachert, Claus, MD, PhD</creator><creator>Hellings, Peter W., MD, PhD</creator><creator>Mullol, Joaquim, MD, PhD, FAAAAI</creator><creator>Gevaert, Philippe, MD</creator><creator>Zhang, Donghui</creator><creator>Khan, Asif</creator><creator>Fan, Chunpeng</creator><creator>Joish, Vijay N</creator><creator>Amin, Nikhil</creator><creator>Pirozzi, Gianluca</creator><creator>Graham, Neil MH</creator><creator>Staudinger, Heribert W., MD</creator><creator>Grabher, Annette</creator><creator>Mannent, Leda</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>20170201</creationdate><title>Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial</title><author>Naclerio, Robert M., MD, FAAAAI ; Hamilos, Daniel L., MD, FAAAAI ; Ferguson, Berrylin J., MD ; Bachert, Claus, MD, PhD ; Hellings, Peter W., MD, PhD ; Mullol, Joaquim, MD, PhD, FAAAAI ; Gevaert, Philippe, MD ; Zhang, Donghui ; Khan, Asif ; Fan, Chunpeng ; Joish, Vijay N ; Amin, Nikhil ; Pirozzi, Gianluca ; Graham, Neil MH ; Staudinger, Heribert W., MD ; Grabher, Annette ; Mannent, Leda</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2285-d1b9aea1285e69eef9817d21c77d6b796b060680bf274f8ed6f7ceecfb6d210b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Allergies</topic><topic>Allergy and Immunology</topic><topic>Nose</topic><topic>Patient assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Naclerio, Robert M., MD, FAAAAI</creatorcontrib><creatorcontrib>Hamilos, Daniel L., MD, FAAAAI</creatorcontrib><creatorcontrib>Ferguson, Berrylin J., MD</creatorcontrib><creatorcontrib>Bachert, Claus, MD, PhD</creatorcontrib><creatorcontrib>Hellings, Peter W., MD, PhD</creatorcontrib><creatorcontrib>Mullol, Joaquim, MD, PhD, FAAAAI</creatorcontrib><creatorcontrib>Gevaert, Philippe, MD</creatorcontrib><creatorcontrib>Zhang, Donghui</creatorcontrib><creatorcontrib>Khan, Asif</creatorcontrib><creatorcontrib>Fan, Chunpeng</creatorcontrib><creatorcontrib>Joish, Vijay N</creatorcontrib><creatorcontrib>Amin, Nikhil</creatorcontrib><creatorcontrib>Pirozzi, Gianluca</creatorcontrib><creatorcontrib>Graham, Neil MH</creatorcontrib><creatorcontrib>Staudinger, Heribert W., MD</creatorcontrib><creatorcontrib>Grabher, Annette</creatorcontrib><creatorcontrib>Mannent, Leda</creatorcontrib><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Journal of allergy and clinical immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Naclerio, Robert M., MD, FAAAAI</au><au>Hamilos, Daniel L., MD, FAAAAI</au><au>Ferguson, Berrylin J., MD</au><au>Bachert, Claus, MD, PhD</au><au>Hellings, Peter W., MD, PhD</au><au>Mullol, Joaquim, MD, PhD, FAAAAI</au><au>Gevaert, Philippe, MD</au><au>Zhang, Donghui</au><au>Khan, Asif</au><au>Fan, Chunpeng</au><au>Joish, Vijay N</au><au>Amin, Nikhil</au><au>Pirozzi, Gianluca</au><au>Graham, Neil MH</au><au>Staudinger, Heribert W., MD</au><au>Grabher, Annette</au><au>Mannent, Leda</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial</atitle><jtitle>Journal of allergy and clinical immunology</jtitle><date>2017-02-01</date><risdate>2017</risdate><volume>139</volume><issue>2</issue><spage>AB90</spage><epage>AB90</epage><pages>AB90-AB90</pages><issn>0091-6749</issn><eissn>1097-6825</eissn><abstract>Rationale Loss of smell is a major consequence for chronic sinusitis patients with nasal polyps and is a severity marker with significant impact on quality of life.</abstract><cop>St. Louis</cop><pub>Elsevier Inc</pub><doi>10.1016/j.jaci.2016.12.245</doi></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0091-6749 |
ispartof | Journal of allergy and clinical immunology, 2017-02, Vol.139 (2), p.AB90-AB90 |
issn | 0091-6749 1097-6825 |
language | eng |
recordid | cdi_proquest_journals_1867963805 |
source | ScienceDirect Journals (5 years ago - present); EZB-FREE-00999 freely available EZB journals |
subjects | Allergies Allergy and Immunology Nose Patient assessment |
title | Dupilumab Improves Sense of Smell and Reduces Anosmia Among Patients with Nasal Polyposis and Chronic Sinusitis: Results from a Phase 2a Trial |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T23%3A14%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dupilumab%20Improves%20Sense%20of%20Smell%20and%20Reduces%20Anosmia%20Among%20Patients%20with%20Nasal%20Polyposis%20and%20Chronic%20Sinusitis:%20Results%20from%20a%20Phase%202a%20Trial&rft.jtitle=Journal%20of%20allergy%20and%20clinical%20immunology&rft.au=Naclerio,%20Robert%20M.,%20MD,%20FAAAAI&rft.date=2017-02-01&rft.volume=139&rft.issue=2&rft.spage=AB90&rft.epage=AB90&rft.pages=AB90-AB90&rft.issn=0091-6749&rft.eissn=1097-6825&rft_id=info:doi/10.1016/j.jaci.2016.12.245&rft_dat=%3Cproquest_cross%3E4313589641%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1867963805&rft_id=info:pmid/&rft_els_id=1_s2_0_S0091674916317638&rfr_iscdi=true |