Role of RhoA/ROCK signaling in lung inflammation and lineage commitment of Mesenchymal stem cells in asthma

Role of RhoA/ROCK signaling in lung inflammation and lineage commitment of Mesenchymal stem cells in asthma

Furthermore, MSC migration and differentiation into myofibroblast was inhibited by Fasudil in MSCs treated with either conditioned medium from CRE-induced human epithelial cells in vitro or CRE-induced chronic mouse model with nestin-GFP mice.

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Veröffentlicht in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB184-AB184
Hauptverfasser: Ke, Xia, Do, Danh C., PhD, Li, Changjun, Zhao, Yilin, MD, PhD, Qu, Jingjing, MD, Wan, Mei, Gao, Peisong, MD, PhD
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Sprache:eng
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Allergy and Immunology
Asthma
Inflammation
Rodents
Stem cells
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container_end_page AB184
container_issue 2
container_start_page AB184
container_title Journal of allergy and clinical immunology
container_volume 139
creator Ke, Xia
Do, Danh C., PhD
Li, Changjun
Zhao, Yilin, MD, PhD
Qu, Jingjing, MD
Wan, Mei
Gao, Peisong, MD, PhD
description Furthermore, MSC migration and differentiation into myofibroblast was inhibited by Fasudil in MSCs treated with either conditioned medium from CRE-induced human epithelial cells in vitro or CRE-induced chronic mouse model with nestin-GFP mice.
doi_str_mv 10.1016/j.jaci.2016.12.602
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source Elsevier ScienceDirect Journals Complete; EZB Electronic Journals Library
subjects Allergy and Immunology
Asthma
Inflammation
Rodents
Stem cells
title Role of RhoA/ROCK signaling in lung inflammation and lineage commitment of Mesenchymal stem cells in asthma
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