Isolated BAL Neutrophilia and Unimodal Airway Epithelial IL-13 Inducible Gene Signatures Characterize Children with Treatment-Resistant Asthma
Unlike studies of adults with milder asthma on low-dose ICS, we could not identify a bimodal pattern of Th2 HIGH and LOW gene expression profiles, likely due to the suppressive effects of high-dose corticosteroid treatment in our sample.
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| Veröffentlicht in: | Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB181-AB181 |
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| container_end_page | AB181 |
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| container_issue | 2 |
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| container_title | Journal of allergy and clinical immunology |
| container_volume | 139 |
| creator | Borish, Larry, MD, FAAAAI Braciale, Thomas J., MD, PhD Shirley, Debbie-Ann, MD Steinke, John W., PhD, FAAAAI Williams, Sandford, MS Pollack, Karlyn, BS Capaldo, Brian J., PhD Teague, W. Gerald, MD |
| description | Unlike studies of adults with milder asthma on low-dose ICS, we could not identify a bimodal pattern of Th2 HIGH and LOW gene expression profiles, likely due to the suppressive effects of high-dose corticosteroid treatment in our sample. |
| doi_str_mv | 10.1016/j.jaci.2016.12.591 |
| format | Article |
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| issn | 0091-6749 1097-6825 |
| language | eng |
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| source | Access via ScienceDirect (Elsevier); EZB Electronic Journals Library |
| subjects | Allergy and Immunology Asthma Gene expression Granulocytes Pathogens |
| title | Isolated BAL Neutrophilia and Unimodal Airway Epithelial IL-13 Inducible Gene Signatures Characterize Children with Treatment-Resistant Asthma |
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