Amyloid-[beta] and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer's disease

This study was designed to test the interaction between amyloid-β and tau proteins as a determinant of metabolic decline in preclinical Alzheimer's disease (AD). We assessed 120 cognitively normal individuals with [18 F]florbetapir positron emission tomography (PET) and cerebrospinal fluid (CSF...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular psychiatry 2017-02, Vol.22 (2), p.306
Hauptverfasser:	Pascoal, T A, Mathotaarachchi, S, Mohades, S, Benedet, A L, Chung, C-o, Shin, M, Wang, S, Beaudry, T, Kang, M S, Soucy, J-p, Labbe, A, Gauthier, S, Rosa-neto, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Alzheimer's disease Amyloidosis Biomarkers Brain research Cognitive ability Dementia Longitudinal studies Medical imaging Metabolism Neurodegeneration Neuroimaging Pathology Pathophysiology Psychiatry Research centers Tomography University research
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!