Synthesis of Novel Tacrine Analogs as Acetylcholinesterase Inhibitors

In this work, a wide range of novel pyrazolo[4′,3′:5,6]pyrano[2,3‐b]quinolin‐5‐amines were synthesized as tacrine analogs. At first, reaction of 3‐methyl‐1‐phenyl‐1H‐pyrazol‐5(4H)‐one, aromatic aldehydes, and malononitrile gave 6‐amino‐4‐aryl‐3‐methyl‐1‐phenyl‐1,4‐dihydropyrano[2,3‐c]pyrazole‐5‐carb...

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Veröffentlicht in:	Journal of heterocyclic chemistry 2017-01, Vol.54 (1), p.384-390
Hauptverfasser:	Mahdavi, Mohammad, Saeedi, Mina, Gholamnia, Laleh, Jeddi, Seyed Amir Behzad, Sabourian, Reyhaneh, Shafiee, Abbas, Foroumadi, Alireza, Akbarzadeh, Tahmineh
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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