Managing Inflammatory Manifestations in Patients with Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by lack of phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which results in inflammatory dysregulation and increased susceptibility to infections. Patients with CGD may develop severe obstructive disorder...

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Veröffentlicht in:	Paediatric drugs 2016-10, Vol.18 (5), p.335-345
Hauptverfasser:	Magnani, Alessandra, Mahlaoui, Nizar
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Causes of Chronic granulomatous disease Complications and side effects Dosage and administration Genetic Therapy - methods Granulomatous Disease, Chronic - therapy Hematopoietic Stem Cell Transplantation - methods Humans Immunosuppressive agents Internal Medicine Medicine Medicine & Public Health NADPH Oxidases - metabolism Patient outcomes Pediatrics Pharmacotherapy Testing Therapy in Practice
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