Non-amyloidogenic effects of [alpha]2 adrenergic agonists: implications for brimonidine-mediated neuroprotection

The amyloid beta (A) pathway is strongly implicated in neurodegenerative conditions such as Alzheimers disease and more recently, glaucoma. Here, we identify the 2 adrenergic receptor agonists (2ARA) used to lower intraocular pressure can prevent retinal ganglion cell (RGC) death via the non-amyloid...

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Veröffentlicht in:	Cell death & disease 2016-12, Vol.7 (12)
Hauptverfasser:	Nizari, Shereen, Guo, Li, Davis, Benjamin M, Normando, Eduardo M, Galvao, Joana, Turner, Lisa A, Bizrah, Mukhtar, Dehabadi, Mohammad, Tian, Kailin, Francesca Cordeiro, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Apoptosis Glaucoma
Online-Zugang:	Volltext
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