Withanolides against TLR4‐Activated Innate Inflammatory Signalling Pathways: A Comparative Computational and Experimental Study

Innate inflammations are dominant causes of poor health and high mortality. The pathogen‐associated molecular pattern and lipopolysaccharide (LPS) are sensed by immune cells through activation of toll‐like receptor 4 leading to mitogen‐activated protein kinases (MAPKs) and NF‐κB activations. Control...

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Veröffentlicht in:Phytotherapy research 2017-01, Vol.31 (1), p.152-163
Hauptverfasser: Purushotham, Preethi M., Kim, Jin‐Man, Jo, Eun‐Kyeong, Senthil, Kalaiselvi
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Sprache:eng
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