Synthesis and Applications of 3-Methylene-4-(trifluoromethyl)azetidin-2-ones as Building Blocks for the Preparation of Mono- and Spirocyclic 4-CF3-[beta]-Lactams

3-Methylene-4-(trifluoromethyl)azetidin-2-ones were efficiently prepared from the corresponding 3-oxo-4-trifluoromethyl-[beta]-lactams and successfully evaluated as novel building blocks in organic synthesis. In particular, Michael additions, electrophilic additions, and cycloadditions were applied...

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Veröffentlicht in:	Asian journal of organic chemistry 2016-12, Vol.5 (12), p.1480
Hauptverfasser:	DaoThi, Hang, Danneels, Barbara, Desmet, Tom, VanHecke, Kristof, VanNguyen, Tuyen, D'hooghe, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Organic chemistry
Online-Zugang:	Volltext
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