An Efficient One-pot Synthesis of Novel Spiro Cyclic 2-Oxindole Derivatives of Pyrimido[4,5-b]Quinoline, Pyrido[2,3-d:6,5-d′]Dipyrimidine and Indeno[2′,1′:5,6]Pyrido [2,3-d]Pyrimidine in Water

A novel and facile one‐pot synthesis of spiro cyclic 2‐oxindole derivatives of pyrimido[4,5‐b]quinoline‐4,6‐dione, pyrido[2,3‐d:6,5‐d′]dipyrimidine‐2,4,6‐trione, and indeno[2′,1′:5,6]pyrido [2,3‐d]pyrimidine employing 6‐aminothiouracil (or 6‐aminouracil), isatin, and cyclic 1,3‐diketone (e.g. 1,3‐in...

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Veröffentlicht in:Journal of heterocyclic chemistry 2016-11, Vol.53 (6), p.2084-2090
Hauptverfasser: Abdelmoniem, Amr Mohamed, Hassaneen, Huwaida M. E., Abdelhamid, Ismail Abdelshafy
Format: Artikel
Sprache:eng
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Zusammenfassung:A novel and facile one‐pot synthesis of spiro cyclic 2‐oxindole derivatives of pyrimido[4,5‐b]quinoline‐4,6‐dione, pyrido[2,3‐d:6,5‐d′]dipyrimidine‐2,4,6‐trione, and indeno[2′,1′:5,6]pyrido [2,3‐d]pyrimidine employing 6‐aminothiouracil (or 6‐aminouracil), isatin, and cyclic 1,3‐diketone (e.g. 1,3‐indanedione, dimedone, or barbituric acid) has been developed.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.2480