Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis

Summary Background Postoperative radiotherapy has an important role in the treatment of prostate cancer, but personalised patient selection could improve outcomes and spare unnecessary toxicity. We aimed to develop and validate a gene expression signature to predict which patients would benefit most...

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Veröffentlicht in:	The lancet oncology 2016-11, Vol.17 (11), p.1612-1620
Hauptverfasser:	Zhao, Shuang G, MD, Chang, S Laura, PhD, Spratt, Daniel E, MD, Erho, Nicholas, MSc, Yu, Menggang, Prof, Ashab, Hussam Al-Deen, MSc, Alshalalfa, Mohammed, PhD, Speers, Corey, MD, Tomlins, Scott A, MD, Davicioni, Elai, PhD, Dicker, Adam P, Prof, Carroll, Peter R, Prof, Cooperberg, Matthew R, MD, Freedland, Stephen J, Prof, Karnes, R Jeffrey, MD, Ross, Ashley E, MD, Schaeffer, Edward M, Prof, Den, Robert B, MD, Nguyen, Paul L, MD, Feng, Felix Y, Dr
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antigens Breast cancer Cancer therapies Combined Modality Therapy DNA Damage Fees & charges Gene expression Hematology, Oncology and Palliative Medicine Humans Laboratories Lymphatic system Male Medical research Metastasis Middle Aged Neoplasm Metastasis Prostate cancer Prostate-Specific Antigen - blood Prostatectomy Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology Prostatic Neoplasms - radiotherapy Prostatic Neoplasms - surgery Radiation therapy Retrospective Studies Transcriptome
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