Back Cover: Discovery and Biophysical Evaluation of First Low Nanomolar Hits Targeting CYP125 of M.tuberculosis

The back cover picture shows the applied screening strategy for the discovery of high affinity hits targeting CYP125, which is a P450 enzyme in Mycobacterium tuberculosis (Mtb). CYP125 plays an important role in cholesterol metabolism of Mtb and could therefore represent a promising novel target for...

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Veröffentlicht in:	ChemMedChem 2016-11, Vol.11 (21), p.2466
Hauptverfasser:	Brengel, Christian, Thomann, Andreas, Schifrin, Alexander, Eberhard, Jens, Hartmann, Rolf W
Format:	Artikel
Sprache:	eng
Schlagworte:	Tuberculosis
Online-Zugang:	Volltext
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