Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections
Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were revie...
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Veröffentlicht in: | American journal of otolaryngology 2016-11, Vol.37 (6), p.523-527 |
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description | Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option. |
doi_str_mv | 10.1016/j.amjoto.2016.08.002 |
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Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.</description><identifier>ISSN: 0196-0709</identifier><identifier>EISSN: 1532-818X</identifier><identifier>DOI: 10.1016/j.amjoto.2016.08.002</identifier><identifier>PMID: 27567384</identifier><identifier>CODEN: AJOTDP</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Age ; Aged ; Aged, 80 and over ; Antibiotics ; Child ; Child, Preschool ; Combined Modality Therapy ; Ear Auricle - abnormalities ; Ear Auricle - microbiology ; Ear Auricle - surgery ; Female ; Glucocorticoids - administration & dosage ; Hospitals ; Humans ; Infant ; Infections ; Inflammation ; Injections, Intralesional ; Male ; Medical records ; Middle Aged ; Otolaryngology ; Pain ; Patients ; Retrospective Studies ; Sinuses ; Surgery ; Treatment Outcome ; Triamcinolone Acetonide - administration & dosage ; Variables ; Young Adult</subject><ispartof>American journal of otolaryngology, 2016-11, Vol.37 (6), p.523-527</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c482t-bd39dbe68bfff5d4ba144897e585e3b97561ac4abbd360f93616df9920a8442b3</citedby><cites>FETCH-LOGICAL-c482t-bd39dbe68bfff5d4ba144897e585e3b97561ac4abbd360f93616df9920a8442b3</cites><orcidid>0000-0002-9590-3477</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.amjoto.2016.08.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27928,27929,45999</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27567384$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chang, Dong Sik</creatorcontrib><creatorcontrib>Lee, Ho Yun</creatorcontrib><creatorcontrib>Choi, Myoung Su</creatorcontrib><creatorcontrib>Song, Kudamo</creatorcontrib><creatorcontrib>Kim, Ah-Young</creatorcontrib><creatorcontrib>Cho, Chin Saeng</creatorcontrib><title>Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections</title><title>American journal of otolaryngology</title><addtitle>Am J Otolaryngol</addtitle><description>Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antibiotics</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Combined Modality Therapy</subject><subject>Ear Auricle - abnormalities</subject><subject>Ear Auricle - microbiology</subject><subject>Ear Auricle - surgery</subject><subject>Female</subject><subject>Glucocorticoids - administration & dosage</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infant</subject><subject>Infections</subject><subject>Inflammation</subject><subject>Injections, Intralesional</subject><subject>Male</subject><subject>Medical records</subject><subject>Middle Aged</subject><subject>Otolaryngology</subject><subject>Pain</subject><subject>Patients</subject><subject>Retrospective Studies</subject><subject>Sinuses</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><subject>Triamcinolone Acetonide - administration & dosage</subject><subject>Variables</subject><subject>Young Adult</subject><issn>0196-0709</issn><issn>1532-818X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU-L1TAUxYM4OM_RbyBScN1606RpshFk8M-DAYWZgXEV0vQGU9tkTFphvv3k8Z4KblyFS37nJOdcQl5RaChQ8XZqzDLFNTZtmRqQDUD7hOxox9paUnn3lOyAKlFDD-qcPM95AgDGWfeMnLd9J3om-Y5824c1mRmzj8HM1U3yZrE-xDkGrPZhQruWm1y5mKr1OxYAzbpgWKvoqq9l2JK322xSde3DlovEnSQvyJkzc8aXp_OC3H78cHP5ub768ml_-f6qtly2az2MTI0DCjk457qRD4ZyLlWPneyQDar8lBrLzVBAAU4xQcXolGrBSM7bgV2QN0ff-xR_bphXPcUtlTBZU8mY4sC6vlD8SNkUc07o9H3yi0kPmoI-9KknfexTH_rUIHXps8hen8y3YcHxj-h3gQV4dwSwRPzlMelsPQaLo0-lCD1G_78X_jWwsw_emvkHPmD-m0XnVoO-Puz0sFIqGFAJgj0CitOerg</recordid><startdate>20161101</startdate><enddate>20161101</enddate><creator>Chang, Dong Sik</creator><creator>Lee, Ho Yun</creator><creator>Choi, Myoung Su</creator><creator>Song, Kudamo</creator><creator>Kim, Ah-Young</creator><creator>Cho, Chin Saeng</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QR</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><orcidid>https://orcid.org/0000-0002-9590-3477</orcidid></search><sort><creationdate>20161101</creationdate><title>Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections</title><author>Chang, Dong Sik ; Lee, Ho Yun ; Choi, Myoung Su ; Song, Kudamo ; Kim, Ah-Young ; Cho, Chin Saeng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c482t-bd39dbe68bfff5d4ba144897e585e3b97561ac4abbd360f93616df9920a8442b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Antibiotics</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Combined Modality Therapy</topic><topic>Ear Auricle - abnormalities</topic><topic>Ear Auricle - microbiology</topic><topic>Ear Auricle - surgery</topic><topic>Female</topic><topic>Glucocorticoids - administration & dosage</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infant</topic><topic>Infections</topic><topic>Inflammation</topic><topic>Injections, Intralesional</topic><topic>Male</topic><topic>Medical records</topic><topic>Middle Aged</topic><topic>Otolaryngology</topic><topic>Pain</topic><topic>Patients</topic><topic>Retrospective Studies</topic><topic>Sinuses</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><topic>Triamcinolone Acetonide - administration & dosage</topic><topic>Variables</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chang, Dong Sik</creatorcontrib><creatorcontrib>Lee, Ho Yun</creatorcontrib><creatorcontrib>Choi, Myoung Su</creatorcontrib><creatorcontrib>Song, Kudamo</creatorcontrib><creatorcontrib>Kim, Ah-Young</creatorcontrib><creatorcontrib>Cho, Chin Saeng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>American journal of otolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chang, Dong Sik</au><au>Lee, Ho Yun</au><au>Choi, Myoung Su</au><au>Song, Kudamo</au><au>Kim, Ah-Young</au><au>Cho, Chin Saeng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections</atitle><jtitle>American journal of otolaryngology</jtitle><addtitle>Am J Otolaryngol</addtitle><date>2016-11-01</date><risdate>2016</risdate><volume>37</volume><issue>6</issue><spage>523</spage><epage>527</epage><pages>523-527</pages><issn>0196-0709</issn><eissn>1532-818X</eissn><coden>AJOTDP</coden><abstract>Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27567384</pmid><doi>10.1016/j.amjoto.2016.08.002</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-9590-3477</orcidid></addata></record> |
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subjects | Adolescent Adult Age Aged Aged, 80 and over Antibiotics Child Child, Preschool Combined Modality Therapy Ear Auricle - abnormalities Ear Auricle - microbiology Ear Auricle - surgery Female Glucocorticoids - administration & dosage Hospitals Humans Infant Infections Inflammation Injections, Intralesional Male Medical records Middle Aged Otolaryngology Pain Patients Retrospective Studies Sinuses Surgery Treatment Outcome Triamcinolone Acetonide - administration & dosage Variables Young Adult |
title | Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections |
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