Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections

Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were revie...

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Veröffentlicht in:American journal of otolaryngology 2016-11, Vol.37 (6), p.523-527
Hauptverfasser: Chang, Dong Sik, Lee, Ho Yun, Choi, Myoung Su, Song, Kudamo, Kim, Ah-Young, Cho, Chin Saeng
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container_end_page 527
container_issue 6
container_start_page 523
container_title American journal of otolaryngology
container_volume 37
creator Chang, Dong Sik
Lee, Ho Yun
Choi, Myoung Su
Song, Kudamo
Kim, Ah-Young
Cho, Chin Saeng
description Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.
doi_str_mv 10.1016/j.amjoto.2016.08.002
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Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.</description><identifier>ISSN: 0196-0709</identifier><identifier>EISSN: 1532-818X</identifier><identifier>DOI: 10.1016/j.amjoto.2016.08.002</identifier><identifier>PMID: 27567384</identifier><identifier>CODEN: AJOTDP</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Age ; Aged ; Aged, 80 and over ; Antibiotics ; Child ; Child, Preschool ; Combined Modality Therapy ; Ear Auricle - abnormalities ; Ear Auricle - microbiology ; Ear Auricle - surgery ; Female ; Glucocorticoids - administration &amp; dosage ; Hospitals ; Humans ; Infant ; Infections ; Inflammation ; Injections, Intralesional ; Male ; Medical records ; Middle Aged ; Otolaryngology ; Pain ; Patients ; Retrospective Studies ; Sinuses ; Surgery ; Treatment Outcome ; Triamcinolone Acetonide - administration &amp; dosage ; Variables ; Young Adult</subject><ispartof>American journal of otolaryngology, 2016-11, Vol.37 (6), p.523-527</ispartof><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c482t-bd39dbe68bfff5d4ba144897e585e3b97561ac4abbd360f93616df9920a8442b3</citedby><cites>FETCH-LOGICAL-c482t-bd39dbe68bfff5d4ba144897e585e3b97561ac4abbd360f93616df9920a8442b3</cites><orcidid>0000-0002-9590-3477</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.amjoto.2016.08.002$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27928,27929,45999</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27567384$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chang, Dong Sik</creatorcontrib><creatorcontrib>Lee, Ho Yun</creatorcontrib><creatorcontrib>Choi, Myoung Su</creatorcontrib><creatorcontrib>Song, Kudamo</creatorcontrib><creatorcontrib>Kim, Ah-Young</creatorcontrib><creatorcontrib>Cho, Chin Saeng</creatorcontrib><title>Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections</title><title>American journal of otolaryngology</title><addtitle>Am J Otolaryngol</addtitle><description>Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Antibiotics</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Combined Modality Therapy</subject><subject>Ear Auricle - abnormalities</subject><subject>Ear Auricle - microbiology</subject><subject>Ear Auricle - surgery</subject><subject>Female</subject><subject>Glucocorticoids - administration &amp; dosage</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infant</subject><subject>Infections</subject><subject>Inflammation</subject><subject>Injections, Intralesional</subject><subject>Male</subject><subject>Medical records</subject><subject>Middle Aged</subject><subject>Otolaryngology</subject><subject>Pain</subject><subject>Patients</subject><subject>Retrospective Studies</subject><subject>Sinuses</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><subject>Triamcinolone Acetonide - administration &amp; 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dosage</topic><topic>Variables</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chang, Dong Sik</creatorcontrib><creatorcontrib>Lee, Ho Yun</creatorcontrib><creatorcontrib>Choi, Myoung Su</creatorcontrib><creatorcontrib>Song, Kudamo</creatorcontrib><creatorcontrib>Kim, Ah-Young</creatorcontrib><creatorcontrib>Cho, Chin Saeng</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>American journal of otolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chang, Dong Sik</au><au>Lee, Ho Yun</au><au>Choi, Myoung Su</au><au>Song, Kudamo</au><au>Kim, Ah-Young</au><au>Cho, Chin Saeng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections</atitle><jtitle>American journal of otolaryngology</jtitle><addtitle>Am J Otolaryngol</addtitle><date>2016-11-01</date><risdate>2016</risdate><volume>37</volume><issue>6</issue><spage>523</spage><epage>527</epage><pages>523-527</pages><issn>0196-0709</issn><eissn>1532-818X</eissn><coden>AJOTDP</coden><abstract>Abstract Objectives The aim of this study is to confirm the effect of adjuvant intralesional triamcinolone acetonide injections (TRIAM) for the treatment of an infected preauricular sinus (PAS). Methods The medical charts of 103 patients diagnosed with PAS from March 2013 to December 2015 were reviewed and documented. The mean duration of treatment and postoperative follow-up period were compared between patients who received TRIAM and patients who received conventional treatment. Results Fifteen patients received TRIAM. The mean duration of treatment was 12.5 ± 11.0 days in patients treated with TRIAM, which was significantly shorter than patients without TRIAM (25.5 ± 25.7 days, p = 0.010). In addition, the percentage of patients experiencing early recovery (within 10 days) was 4.15 times higher with TRIAM (95% confidence interval: 1.07–16.13, p = 0.040). The mean postoperative follow-up period revealed a similar tendency; patients treated with TRIAM required a shorter follow-up period (8 ± 2.6 days) than patients not treated with TRIAM (13.5 ± 7.4 days). However, this difference was not significant ( p = 0.242). Conclusion Although the sample was small, patients with PAS infections who were treated with TRIAM as an adjuvant therapy required a significantly shorter treatment duration than patients receiving conventional treatment alone. This finding suggests a beneficial effect of TRIAM for the short-term control of PAS infections. Clinicians should consider TRIAM as an adjuvant treatment option.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27567384</pmid><doi>10.1016/j.amjoto.2016.08.002</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-9590-3477</orcidid></addata></record>
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subjects Adolescent
Adult
Age
Aged
Aged, 80 and over
Antibiotics
Child
Child, Preschool
Combined Modality Therapy
Ear Auricle - abnormalities
Ear Auricle - microbiology
Ear Auricle - surgery
Female
Glucocorticoids - administration & dosage
Hospitals
Humans
Infant
Infections
Inflammation
Injections, Intralesional
Male
Medical records
Middle Aged
Otolaryngology
Pain
Patients
Retrospective Studies
Sinuses
Surgery
Treatment Outcome
Triamcinolone Acetonide - administration & dosage
Variables
Young Adult
title Intralesional Triamcinolone Injections for the Treatment of Preauricular Sinus Infections
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